Juvenile Idiopathic Arthritis: Review of the Literature and Case Report

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Tags: Literature Review Source Type: research

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ABSTRACT OBJECTIVE To assess the prevalence and factors associated with falls in a nationally representative sample of older Brazilians residing in urban areas. METHODS Data from 4,174 participants (60 years or older) from the baseline of ELSI-Brazil, conducted between 2015 and 2016, were used. The outcome variable was the reporting of one or more falls in the last 12 months. The exploratory variables were sociodemographic characteristics, factors related to the urban environment, and health conditions. Statistical analysis was performed using Poisson regression. RESULTS The prevalence of falls was 25.1%. Of these, 1.8% re...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
ABSTRACT Recognizing the semiologic importance of the second, and most famous, sign described by Joseph Babinski – the extension of the hallux after stimulation of the plantar region in order to differentiate organic from pithiatic paralysis – several authors have tried to find a comparable signal in the hand. After 122 years, no one has succeeded.RESUMO Reconhecida a import ância semiológica do segundo e mais famoso sinal descrito por Joseph Babinski - a extensão do hálux após estimulo plantar visando diferenciar a paralisia orgânica da pitiática - diversos autore...
Source: Arquivos de Neuro-Psiquiatria - Category: Neurology Source Type: research
Conclusions: QoL and sexual function were altered in women with psoriasis and should be taken into consideration when assessing disease severity.
Source: Anais Brasileiros de Dermatologia - Category: Dermatology Source Type: research
Authors: Serra López-Matencio JM, Morell Baladrón A, Castañeda S Abstract The Janus kinase (JAK) pathway is implicated in the pathogenesis of many inflammatory and autoimmune diseases including rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease. There are a lot of proinflammatory cytokines involved in such diseases using this pathway to transduce intracellular signals. In the last years, JAK inhibitors (jakinibs) have appeared with a great success, showing that these kinds of drugs have a great applicability in clinical practice. Tofacitinib and baricitinib, the first jakinibs...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Kip Burgess was relieved last year when pharmaceutical giant Amgen overnighted him a $2,976 check to help pay for his go-to arthritis drug, Enbrel. The 36-year-old psychologist had run into an increasingly common problem: The copay coupon sent by Amgen couldn’t cover the drug’s more than $4,000 monthly price. “Nothing in the world gives me more anxiety than just getting my medication,” Burgess said. “There’s nothing you can do but beg.” Panicked, Burgess had called Amgen and pleaded for help. The drugmaker sent him the check after he provided a credit card statement and an explanat...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs Source Type: news
Condition:   Juvenile Idiopathic Arthritis Interventions:   Drug: Baricitinib;   Drug: Placebo Sponsor:   Eli Lilly and Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Juvenile Idiopathic Arthritis Intervention:   Drug: Baricitinib Sponsor:   Eli Lilly and Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Rheumatoid Arthritis Intervention:   Behavioral: Mobile Health App Sponsor:   Mayo Clinic Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: 11 December 2018Source: Cell Reports, Volume 25, Issue 11Author(s): S. Saif Hasan, Chengqun Sun, Arthur S. Kim, Yasunori Watanabe, Chun-Liang Chen, Thomas Klose, Geeta Buda, Max Crispin, Michael S. Diamond, William B. Klimstra, Michael G. RossmannSummaryAlphaviruses are enveloped pathogens that cause arthritis and encephalitis. Here, we report a 4.4-Å cryoelectron microscopy (cryo-EM) structure of eastern equine encephalitis virus (EEEV), an alphavirus that causes fatal encephalitis in humans. Our analysis provides insights into viral entry into host cells. The envelope protein E2 showed a binding s...
Source: Cell Reports - Category: Cytology Source Type: research
CONCLUSIONS: There was no conclusive evidence found regarding correlation between TMJ clinical signs and radiological features of osseous destruction in patients with JIA - only weak correlation between pain and condyle surface flattening was observed. The number of clinical TMJ signs does not correlate with number of radiological features. For the clinical decision both clinical examination and CBCT would be useful in the early detection of osseous destruction of the TMJ in JIA patients. PMID: 30531162 [PubMed - in process]
Source: Stomatologija - Category: Dentistry Tags: Stomatologija Source Type: research
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