Paracetamol poisoning-related hospital admissions and deaths in Australia, 2004-2017 - Cairns R, Brown JA, Wylie CE, Dawson AH, Isbister GK, Buckley NA.

OBJECTIVES: To assess the numbers of paracetamol overdose-related hospital admissions and deaths in Australia since 2007-08, and the overdose size of intentional paracetamol overdoses since 2004. DESIGN, SETTING: Retrospective analysis of data on paracetam...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

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AbstractPurpose of ReviewThis review describes case reports for patients with kratom-associated adverse events in order to assist clinicians with patient management. A stepwise approach is proposed for assessing active kratom users as well as considerations for the management of toxicities or withdrawal.Recent FindingsMultiple in vitro and in vivo studies illustrate the pharmacologic and toxicologic effects of kratom extract. No randomized controlled trials in humans exist that assess the safety and efficacy of the substance. Cross-sectional surveys from active users and reports from poison control centers have shown acute...
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
Americans are dying form accidental overdoses at an alarming rate.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
The news that somebody at a West Virginia VA medical center wasapparently murdering patients with insulin overdoses is the latest reminder of a phenomenon that occurs disturbingly often. The denominator of all the medical professionals in the world is obviously very large, so the dozens who have been identified as serial killers don't mean you are at notable risk, but still. Actually there must be many more since one of the perks of being a physician or a nurse is that you can get away with being a serial killer pretty easily.The most notorious is probably the British GP Harold Shipman,who killed at least 218 of his own pa...
Source: Stayin' Alive - Category: American Health Source Type: blogs
The U.S. Centers for Disease Control and Prevention is investigating a growing number of “severe” lung disease cases that appear to be related to vaping. Since late June, according to the CDC, 94 people in 14 states have come down with serious lung illnesses that may be linked to use of e-cigarettes, which heat substances including nicotine and cannabis to create aerosols that users inhale. The case count has grown high enough to prompt the CDC to work with state health departments to learn more about what could be causing the worrisome conditions, which are primarily affecting adolescents. Although “mor...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
The U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are investigating a growing number of “severe” lung disease cases that appear to be related to vaping. The CDC first announced on Saturday that it would help state health departments investigate a concerning number of serious lung illnesses apparently linked to use of e-cigarettes, which heat substances including nicotine and cannabis to create aerosols that users inhale. At that time, 94 cases in 14 states had been reported—but as of Wednesday, according to a CDC statement, the number had ballooned to 153...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
The U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are investigating a growing number of “severe” lung disease cases that appear to be related to vaping. The CDC first announced on Saturday that it would help state health departments investigate a concerning number of serious lung illnesses apparently linked to use of e-cigarettes, which heat substances including nicotine and cannabis to create aerosols that users inhale. At that time, 94 cases in 14 states had been reported—but as of Friday, according to a CDC statement, the number had ballooned to 149 po...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
CONCLUSIONS: The frequency of paracetamol overdose-related hospital admissions has increased in Australia since 2004, and the rise is associated with greater numbers of liver injury diagnoses. Overdose size and the proportion of overdoses involving modified release paracetamol have each also increased. PMID: 31389025 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
CONCLUSIONS: It is reassuring that the absolute number of prescription drug suicides in non-abusers was small; the findings, however, are important because they could serve as a baseline for assessing time trends in future studies. For the present, we suggest that prescription drugs of potential abuse, especially those containing opioids and antispasmodics, should be prescribed and dispensed judiciously, especially to youth. PMID: 31374376 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
ng Lijun Li The detection of difenidol hydrochloride, which is a drug that is widely used for treating the nausea and vomiting symptoms caused by certain diseases, has been increasingly involved in cases of suicide via overdosing and of drug poisoning in children. A novel electrochemiluminescence (ECL) sensor for the simple and effective detection of difenidol hydrochloride was fabricated by modifying a glassy carbon electrode with three-dimensional carbon nanofibers (3D-CNFs). The 3D-CNFs were synthesized by electrospinning a mixture of montmorillonite (MMT) and polyacrylonitrile, carbonizing the electrospun product...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
Authors: Yaylac─▒ F, Küçük Ö, Erkuran HÖ Abstract Paliperidone is a relatively novel atypical antipsychotic drug that is currently used to treat schizophrenia in adolescents and adults. The drug was generated by combining the active metabolite of risperidone, 9-hydroxyrisperidone, with osmotic controlled-release oral administration system (OROS) technology. Due to its specific design, the drug has been identified as a different form, albeit an active metabolite of risperidone. Such distinction mainly manifests itself during pharmacokinetic processes, because paliperidone is not affected b...
Source: Psychopharmacology Bulletin - Category: Psychiatry & Psychology Tags: Psychopharmacol Bull Source Type: research
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