Practical method for increasing optical purity of cis-verbenol.

Practical method for increasing optical purity of cis-verbenol.
Chirality. 2019 Aug 08;:
Authors: Kovalenko V, Krauchanka A, Prokhorevich K
Abstract
R/S mixture of monoterpene alcohol cis-verbenol can be separated in preparative scale by its conversion into phthalic mono-ester and subsequent crystallization of its diastereomeric salts with (R)-α-methylbenzylamine and (S)-α-methylbenzylamine. Finally, basic methanolysis of the resolved phthalic mono-esters results (S)-cis-verbenol and (R)-cis-verbenol in high enantiomeric and diastereomeric purity.
PMID: 31393641 [PubMed - as supplied by publisher]

Source: Chirality - August 7, 2019 Category: Molecular Biology Authors: Kovalenko V, Krauchanka A, Prokhorevich K Tags: Chirality Source Type: research