Bicoid-Dependent Activation of the Target Gene hunchback Requires a Two-Motif Sequence Code in a Specific Basal Promoter

Ling et  al. identify a two-motif sequence code that is required and sufficient for activation of a specific promoter by the transcription factor Bicoid. They suggest that binding a single factor to both enhancers and promoters increases the probability that they will interact.

Source: Molecular Cell - August 7, 2019 Category: Cytology Authors: Jia Ling, Kristaley Yui Umezawa, Theresa Scott, Stephen Small Tags: Article Source Type: research