Excellent restoration of left ventricular compliance after prolonged del Nido single-dose cardioplegia in an in vivo piglet model

The objective is to evaluate the left ventricular (LV) function recovery and accompanying biochemical and histological markers to clarify the tolerable ischemic time in an in vivo cardiopulmonary bypass (CPB) piglet model. Twenty-one piglets were subjected to either 90 min (with or without topical cooling; TC) or 120 min (with TC) of global ischemia induced by single-dose DN while the other seven served as the control group (CPB only).
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ADULT – Original Submission Source Type: research