Cytotoxic ergosterols from cultures of the basidiomycete Psathyrella candolleana.

Cytotoxic ergosterols from cultures of the basidiomycete Psathyrella candolleana.
Fitoterapia. 2019 Aug 03;:104289
Authors: Liu YP, Pu CJ, Wang M, He J, Li ZH, Feng T, Xie J, Liu JK
Abstract
Three newly isolated ergosterols, psathergosterols A-C (1-3), together with two known ones (4 and 5), have been isolated from cultures of the basdiomycete Psathyrella candolleana. Their structures with the absolute configuration were elucidated by means of spectroscopic methods and the single crystal X-ray diffraction. Compounds 2-4 exhibited certain cytotoxicities to five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW480).
PMID: 31386896 [PubMed - as supplied by publisher]

Source: Fitoterapia - August 2, 2019 Category: Biochemistry Authors: Liu YP, Pu CJ, Wang M, He J, Li ZH, Feng T, Xie J, Liu JK Tags: Fitoterapia Source Type: research