The Continuing Relevance of Leprosy

After the introduction of multidrug therapy (MDT) for leprosy in 1981, there was an impressive reduction in the number of cases worldwide, from an estimated 5.2 million in 1985 to 193  069 in 2017. Approximately 16 million people were treated with MDT, provided free of cost since 1995 by the World Health Organization (WHO). In 2000, the global prevalence dropped below 1 per 10 000 people, an arbitrarily chosen threshold at which it was believed that there would be too few cas es to sustain transmission in the community. This target was subsequently achieved at a national level by nearly all the countries of the world in 2005. It was easy to believe, as many did, that this ancient scourge first described in Indian medical texts dating to about 1500 BCE was in its last thr oes.
Source: JAMA Dermatology - Category: Dermatology Source Type: research

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Conclusions/SignificanceOur finding suggests that synergetic associations of activating and inhibitoryKIR genes may alter the balance between these receptors and thus interfere in the progression of multibacillary leprosy.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Publication date: Available online 12 September 2019Source: Biosensors and BioelectronicsAuthor(s): Archana Kushwaha, Juhi Srivastava, Ambareesh Kumar Singh, Richa Anand, Richa Raghuwanshi, Tulika Rai, Meenakshi SinghAbstractMycobacterium leprae causes endemic disease leprosy which becomes chronic if not treated timely. To expedite this ‘timely diagnosis’, and that also at an early stage, here an attempt is made to fabricate an epitope-imprinted sensor. A molecularly imprinted polymer nanoparticles modified electrochemical quartz crystal microbalance sensor was developed for sensing of mycobacterium leprae bact...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
CONCLUSION: Imported cases of leprosy are responsible for most leprosy incidence in Italy, and social stigma, the unfamiliarity of healthcare professionals with such disorders, and difficulties of some high-risk groups to be appropriately assessed hint to a possible under-diagnosis. Professionals should be made more aware of the potential for leprosy incidence among patients from countries where the disease is endemic. PMID: 31517884 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
The 20th International Leprosy Congress (ILC) is being held Sept. 10 to 13 in Manila, Philippines. The conference is hosted every three years and was last held in China in 2016. Credit: Stella Paul/IPS By Stella PaulMANILA, Sep 12 2019 (IPS) Rachna Kumari of Munger in Eastern India’s Bihar state is not yet 30. But she’s already been married at 18, abandoned by her husband after she was diagnosed with leprosy and become an award-winning advocate of the disease. She has traversed a long road. And this week she undertook another step in her journey to fly to Manila, Philippines, as a delegate at the 20th Internati...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Asia-Pacific Civil Society Conferences Development & Aid Featured Global Headlines Health Human Rights Regional Categories TerraViva United Nations Global Forum of People’s Organisations on Hansen’s Disease Ni Source Type: news
Conclusions: The downward trend in mortality from NTDs is significant for both sexes. It is clear that despite the decline in recent years, mortality from NTDs is an important public health problem. PMID: 31497035 [PubMed]
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
ConclusionsIn summary, this paper represents a series of ocular leprosy cases from the AFIP which shows the severity of ocular involvement, the predilection of anterior segment involvement and a large number of histopathologic indeterminate cases. The current immigrant and refugee crisis warrants revisting this ancient disease in the differential diagnosis.
Source: Saudi Journal of Ophthalmology - Category: Opthalmology Source Type: research
Yohei Sasakawa, chair of The Nippon Foundation and World Health Organisation (WHO) Goodwill Ambassador for Leprosy Elimination, delivered a keynote address at the 20th International Leprosy Congress (ILC). Credit: Stella Paul/IPSBy Stella PaulMANILA, Sep 11 2019 (IPS) Forty years ago, Yohei Sasakawa saw his father moved to tears after meeting and witnessing the suffering of people affected by leprosy – also known as Hansen’s disease. Not only did the patients have a physical illness, but they also suffered from social exclusion and discrimination. It made the young Sasakawa vow to work for the elimination of le...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Aid Asia-Pacific Civil Society Conferences Development & Aid Editors' Choice Featured Global Headlines Health Human Rights Regional Categories TerraViva United Nations Global Forum of People’s Organisations on Source Type: news
Jennifer Quimno of the Coalition of Leprosy Advocates of the Philippines (CLAP) (centre) is joined by Sri Lanka's Shagana Thiygalingam (L) and Amarasinghe Manjula (R) after Quimno delivered the recommendations presented by the Global Forum of People's Organisations on Hansen's Disease to the International Leprosy Congress in Manila on September 11. Credit: Ben Kritz/IPSBy Ben KritzMANILA, Sep 11 2019 (IPS) Stronger government action to fight stigma and discrimination, more government funding for health and non-health support programmes, and a larger role for people’s organisations in developing policy towards Hansen&...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Civil Society Conferences Development & Aid Featured Global Headlines Health Human Rights Regional Categories TerraViva United Nations Global Forum of People’s Organisations on Hansen’s Disease Hansen's disease N Source Type: news
Her experience and the chance "to help strengthen Colombia, the world, and my family" through participating in the Global Forum of People's Organisations on Hansen's Disease, sponsored by the Nippon Foundation and the Sasakawa Health Foundation, was like "rising from the ashes" for Lucrecia Vazques from Felehansen Colombia. Vazques' family was hit hard by leprosy, with not only herself, but her son and one-month-old granddaughter being afflicted. Credit: Ben Kritz/IPSBy Ben KritzMANILA, Sep 10 2019 (IPS) The Global Forum of People’s Organisations on Hansen’s Disease, which was attended by me...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Asia-Pacific Civil Society Conferences Development & Aid Featured Global Headlines Health Human Rights Regional Categories Sustainability TerraViva United Nations Global Forum of People’s Organisations on Hansen Source Type: news
By Stella PaulMANILA, Sep 10 2019 (IPS) Octogenarian Yohei Sasakawa has travelled to more than 90 countries across the globe; from areas of conflict, to the jungles of Brazil, shaking hands, hugging and washing the feet of Hansen’s disease-affected people. His message is simple: Stop stigmatisation and eliminate the disease. Sasakawa, who has spent more than 40 years working towards elimination of Hansen’s disease, is the World Health Organization’s (WHO) Goodwill Ambassador for Leprosy Elimination and chairperson of The Nippon Foundation (TNF). Since 1975, TNF and its sister organisation, the Sasakawa He...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Civil Society Conferences Development & Aid Editors' Choice Featured Global Headlines Health Human Rights Multimedia Regional Categories TerraViva United Nations Video Global Forum of People’s Organisations on Ha Source Type: news
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