Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease.

DISCUSSION: While CSF tau and lower baseline MMSE association with seizure development could in part be explained by a greater degree of cortical damage, the role of tau in the modulation of neuronal excitability may also play a role and should be further investigated. PMID: 31382178 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31382178?dopt=Abstract

Source: Epilepsy and Behaviour - August 1, 2019 Category: Neurology Authors: Tábuas-Pereira M, Durães J, Lopes J, Sales F, Bento C, Duro D, Santiago B, Almeida MR, Leitão MJ, Baldeiras I, Santana I Tags: Epilepsy Behav Source Type: research