Enhanced Programmed Death 1 and Diminished Programmed Death Ligand 1 Up ‐Regulation Capacity of Post‐Activated Lupus B Cells

ConclusionPost ‐activated, hyporesponsive lupus B cells are characterized by a phenotype of increased PD‐1, functionally diminished PD‐L1 up‐regulation capacity, and reduced proliferation upon stimulation.

Source: Arthritis and Rheumatology - August 5, 2019 Category: Rheumatology Authors: Ana ‐Luisa Stefanski, Annika Wiedemann, Karin Reiter, Falk Hiepe, Andreia C. Lino, Thomas Dörner Tags: Brief Report Source Type: research