Oral modified release morphine for breathlessness in chronic heart failure: a randomized placebo ‐controlled trial

ConclusionsWe could not answer our primary objectives due to inadequate power. However, we provide novel placebo ‐controlled medium‐term benefit and safety data useful for clinical practice and future trial design. Morphine should only be prescribed in this population when other measures are unhelpful and with early management of side effects.

Source: ESC Heart Failure - August 5, 2019 Category: Cardiology Authors: Miriam J. Johnson, Sarah Cockayne, David C. Currow, Kerry Bell, Kate Hicks, Caroline Fairhurst, Rhian Gabe, David Torgerson, Laura Jefferson, Stephen Oxberry, Justin Ghosh, Karen J. Hogg, Jeremy Murphy, Victoria Allgar, John G.F. Cleland, A Tags: Original Research Article Source Type: research