Sensitivity of the Candida albicans trehalose-deficient mutants tps1 Δ and tps2Δ to amphotericin B and micafungin.

CONCLUSION: Our data lend weight to the idea of using trehalose biosynthesis as a potential target for antifungal therapy.
PMID: 31380734 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - August 4, 2019 Category: Microbiology Authors: Guirao-Abad JP, Pujante V, Sánchez-Fresneda R, Yagüe G, Argüelles JC Tags: J Med Microbiol Source Type: research