Venetoclax in Immunoglobulin Light Chain Amyloidosis: Is This the Beginning or the End?

Immunoglobulin light chain amyloidosis (AL) is a plasma cell (PC) dyscrasia characterized by a neoplastic malignant PC population producing highly toxic light chains. Despite overlapping features with multiple myeloma (MM), therapeutic options are limited as a result of disease-specific treatment toxicities. Given delays in diagnosis, patients often present with advanced disease, making them poor candidates for autologous stem-cell transplantation.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Case Report Source Type: research