Depth-of-interaction study of a dual-readout detector based on TOFPET2 application-specific integrated circuit.

Depth-of-interaction study of a dual-readout detector based on TOFPET2 application-specific integrated circuit.
Phys Med Biol. 2019 Aug 05;:
Authors: Li M, Abbaszadeh S
Abstract
Depth-of-interaction (DOI) capability is important for achieving high spatial resolution and sensitivity in dedicated organ and small animal positron emission tomography (PET) scanners. The dual-ended readout is one of the common methods that can achieve good DOI resolution. The aim of this study is to evaluate a dual-ended readout detector based on silicon photomultiplier (SiPM) and TOFPET2 application- specific integrated circuit (ASIC). The detector is based on 4×4 lutetium-yttrium oxyorthosilicate (LYSO) units, each unit contained 6×6 LYSO pixels, and the pixel size was 1×1×20 mm3. The four lateral surfaces of LYSO pixels were mechanically ground to W14 (surface roughness 10 to 14 μm), and the two ended surfaces were polished (surface roughness < 0.5 μm). The reflector was Toray Lumirror E60, and the packing fraction of the LYSO block was 86.5%. Each LYSO unit was read out from both ends with two Hamamatsu S13361-3050AE-08 SiPM arrays. The analog output signals of SiPM were digitized by PETsys TOFPET2 ASIC and acquired by PETsys SiPM Readout System. The ASIC and SiPM were cooled by a fan and a Peltier element. To investigate the crystal resolvability, different light guide thicknesses including 0.8, 1, 1.2 and 2 mm were tested. Th flight ...

Source: Physics in Medicine and Biology - August 4, 2019 Category: Physics Authors: Li M, Abbaszadeh S Tags: Phys Med Biol Source Type: research