Shock, aortic occlusion and creamy plasma

Acute occlusion of the abdominal aorta is an extremely rare disease. A 31-year-old man with history of neuroblastoma of the left adrenal gland in childhood treated with radiotherapy, chemotherapy and surgery was known to have secondary arterial hypertension due to renal artery stenosis. He also had poor alimentary habits with excessive alcohol and massive sugar consumption. He presented to hospital for acute bilateral limb ischemia with complete paralysis. Abdominal CT-scan revealed abdominal aortic occlusion below the renal arteries, associated with severe pancreatitis (plasma lipase  = 1459 UI/l) (Fig.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research

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Little is known regarding the association between alcohol use and violence among community college women. Accordingly, this study investigated daily-level associations between alcohol use and intimate partner victimization (IPV) in a sample of young women ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Conclusions: There is a risk of leptospira infections having a late diagnosis given their unspecific clinical presentation, which generates a high number of differential diagnoses. The early management in the intensive care unit could decrease the incidence of complications and the mortality of patients with leptospirosis. PMID: 31529853 [PubMed - in process]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
CONCLUSIONS: Caregivers are engaging in a range of health risk behaviours; however, rates of hazardous alcohol consumption among the sample were high. Health promotion interventions targeted to address alcohol consumption should consider caregiver age and country of residence. So what? This study highlights the health risk behaviours caregivers engage in across a number of countries, and suggests that caregivers require further support to manage alcohol consumption in particular. PMID: 31529552 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
SAN DIEGO - Photon-counting CT scanners might not yet be available for everyday...Read more on AuntMinnie.comRelated Reading: Dedicated breast CT shows promise for cancer screening Photon-counting breast CT shows promise ISCT: New CT detectors promise sharper images NIH begins clinical use of photon-counting CT MDCT: Future CT scanners will deliver more image, less noise
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Authors: Wei L, Osman S, Hatt M, El Naqa I Abstract Due to the recent developments of both hardware and software technologies, multimodality medical imaging techniques have been increasingly applied in clinical practice and research studies. Previously, the application of multimodality imaging in oncology has been mainly related to combining anatomical and functional imaging to improve diagnostic specificity and/or target definition, such as positron emission tomography/computed tomography (PET/CT) and single-photon emission computed tomography (SPECT)/CT. More recently, the fusion of various images, such as multi-...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Authors: Bogowicz M, Vuong D, Huellner MW, Pavic M, Andratschke N, Gabrys HS, Guckenberger M, Tanadini-Lang S Abstract Today, rapid technical and clinical developments result in an increasing number of treatment options for oncological diseases. Thus, decision support systems are needed to offer the right treatment to the right patient. Imaging biomarkers hold great promise in patient-individual treatment guidance. Routinely performed for diagnosis and staging, imaging datasets are excepted to hold more information than used in the clinical practice. Radiomics describes the extraction of a large number of meaningfu...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Abstract From the time it was conceptualized in 1998 to the present, RNAS+ has largely concentrated on research that will generate results to facilitate control, prevention and elimination of its target diseases. Diagnostics has remained an active field of research in order to develop tools that are appropriate for each stage from the first efforts until attempts to block transmission. For example, with regard to schistosomiasis, chemotherapy has excellent impact on morbidity, while better diagnostics and vaccine research have been promoted to complement the other components of the control programme. The need for ...
Source: Advances in Parasitology - Category: Parasitology Authors: Tags: Adv Parasitol Source Type: research
Publication date: Available online 14 September 2019Source: International Journal of PharmaceuticsAuthor(s): Alice Melocchi, Marco Uboldi, Nicoletta Inverardi, Francesco Briatico-Vangosa, Francesco Baldi, Stefano Pandini, Giulia Scalet, Ferdinando Auricchio, Matteo Cerea, Anastasia Foppoli, Alessandra Maroni, Lucia Zema, Andrea GazzanigaAbstractSeveral diseases would benefit from prolonged drug release provided by systems retained in the stomach for extended time periods. Expandable gastroretentive devices are administered in a collapsed configuration enabling swallowing and regain in situ their native shape having larger ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 13 September 2019Source: International Journal of PharmaceuticsAuthor(s): Rasmus Blaaholm Nielsen, Ariane Kahnt, Lieve Dillen, Koen Wuyts, Jan Snoeys, Ulla Gro Nielsen, René Holm, Carsten Uhd NielsenAbstractIn the small intestine, P-glycoprotein (P-gp) may limit the permeability of its substrates, which lead to reduced oral absorption. To circumvent the effect of P-gp, a nanocomposite material termed montmorillonite-surfactant hybrid particles was developed. The particles consisted of montmorillonite, the P-gp-inhibiting, nonionic surfactant, polysorbate 20, and the P-gp substrate,...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 13 September 2019Source: International Journal of PharmaceuticsAuthor(s): Jieying Cai, Shiwen Luo, Xueli Lv, Yingguang Deng, Hongyuan Huang, Boxin Zhao, Qing Zhang, Guofeng LiAbstractTo develop a new drug delivery system is one of the useful approaches to break through the limitation of hydroxycamptothecin (HCPT), a typical DNA topoisomerase I (Topo I) inhibitor in clinical appliance. Injectable glycyrrhizic acid-hydroxycamptothecin (GL-HCPT) micelles that were able to dramatically improve the solubility and stability of HCPT were prepared through self-assembly process and evaluated both ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
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