Neurologic injuries following road traffic accidents in the Dominican Republic: Examining causes and potential solutions.

This study examines RTA-related TBIs in the Dominican Republic, a country in the Caribbean with the highest RTA fatality rate in the Western Hemisphere. Methods: We interviewed 117 adult patients or medical guardians of patients admitted to Hospital Traumatológico Dr. Ney Arias Lora in Santo Domingo following an RTA. Information regarding the type of accident, patient demographics, and injuries sustained was collected for each patient. Results: Most study participants were males (79.5%), and the most common method of transportation was motorized 2-wheeled vehicle (MTW; 74.4%). Of the 69 patients who suffered a TBI, 66.7% were classified as moderate-severe TBIs and 30.3% were classified as mild TBIs. The most common types of intracranial hemorrhage were subdural hemorrhage (12%) and subarachnoid hemorrhage (9.4%). Helmet use among admitted MTW riders was reported at 22.4%, and none of the 9 MTW riders who died in the hospital were wearing a helmet. Only 58.1% of patients lived in an area that offered 911 emergency response services at the time of the study. At 66.2%, the majority of people living within the 911 service area utilized emergency response services following an RTA. Multiple logistic regression determined that the utilization of 911 emergency response services was associated with a decrease in the likelihood of presenting with a moderate/severe TBI by a factor of 0.78 (adjusted odds ratio [OR]; P 
Source: Traffic Injury Prevention - Category: Accident Prevention Authors: Tags: Traffic Inj Prev Source Type: research

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AbstractTranslational genomics represents a broad field of study that combines genome and transcriptome-wide studies in humans and model systems to refine our understanding of human biology and ultimately identify new ways to treat and prevent disease. The approaches to translational genomics can be broadly grouped into two methodologies, forward and reverse genomic translation. Traditional (forward) genomic translation begins with model systems and aims at using unbiased genetic associations in these models to derive insight into biological mechanisms that may also be relevant in human disease. Reverse genomic translation...
Source: Neurotherapeutics - Category: Neurology Source Type: research
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Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
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Source: Medgadget - Category: Medical Devices Authors: Tags: Emergency Medicine Neurology Neurosurgery Radiology Source Type: blogs
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Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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Source: International Journal of Rehabilitation Research - Category: Rehabilitation Tags: Original Articles Source Type: research
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Source: Shock - Category: Emergency Medicine Tags: Review Articles Source Type: research
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Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
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Source: Neurocritical Care - Category: Neurology Source Type: research
Although qualitative or semiquantitative clinical grades (such as WFNS grade and modified Fisher grade) are well known to be associated with DCI following aSAH, identification of an easily measurable and more objective biomarker for predicting DCI might be helpful for early prediction and risk mitigation. In the current study, we found that the early stage neuroglobin level was a significant predictor of DCI in aSAH patients. Furthermore, combined use of WFNS grade and Ngb level might be able to better identify aSAH patients with high risk of DCI. AbstractBackgroundThe neuroglobin (Ngb) is well recognized as a potential bi...
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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