Low doses of ionizing radiation activate endothelial cells and induce angiogenesis in peritumoral tissues.

CONCLUSIONS: LDIR activate ECs in peritumoral tissues that are associated with increased MVD. Although the technological advances in radiotherapy have contributed to reduce the damage to healthy tissues over the past years, the anatomical regions receiving LDIR should be taken into account in the treatment plan report for patient follow-up and in future studies to correlate these doses with tumor dissemination. PMID: 31376927 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31376927?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - July 30, 2019 Category: Radiology Authors: Gil Marques F, Poli E, Malaquias J, Carvalho T, Portêlo A, Ramires A, Aldeia F, Ribeiro RM, Vitorino E, Diegues I, Costa L, Coutinho J, Pina F, Mareel M, Constantino Rosa Santos S Tags: Radiother Oncol Source Type: research