Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration.

CONCLUSIONS: This study identified a rare, functional promoter variant in the PGF gene that increases PGF transcription activity and confers a 5-fold risk to neovascular AMD.
PMID: 31377148 [PubMed - as supplied by publisher]

Source: Experimental Eye Research - July 31, 2019 Category: Opthalmology Authors: Ma L, Ng TK, Chen H, Brelén ME, Lai TYY, Ho M, Tam POS, Young AL, Chen W, Tham CC, Pang CP, Chen LJ Tags: Exp Eye Res Source Type: research