Man who received nation's first 'breathing lung' transplant at UCLA thankful for gift of life

  Fernando Padilla could barely breathe or walk more than a few steps. An incurable disease, pulmonary fibrosis, was causing his lungs to turn to hardened scar tissue, and he was permanently tethered to an oxygen tank. His only hope was a double lung transplant.   In November 2012, he got an early-morning call that a pair of donor lungs was available.   Upon arriving at Ronald Reagan UCLA Medical Center, he was told of a new study testing an experimental device — a portable organ-preservation system that keeps donor lungs functioning and "breathing" in a near-physiologic state outside the body during transport to a recipient, instead of the standard method, in which the organs are kept in an icebox in a non-functioning, non-breathing state.    Padilla consented to participate in the study and was randomized to become the first patient at UCLA — and in the United States — to undergo the 'breathing lung' transplant using the TransMedics Organ Care System (OCS).   "If they've got new technology to deliver the lungs still breathing, I think that would be better than trying to wake them back up again after being on ice," said the former construction worker, who had helped build the very same hospital where he was now a patient. "I'm just following technology."   With the OCS, the lungs are removed from a donor's body and are placed in a mobile high-tech box, where they are immediately revived to a w...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
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Source: Biomedical and Environmental Sciences - Category: Biomedical Science Source Type: research
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Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
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Source: - Category: Research Source Type: clinical trials
We describe the case of a 55-year old patient with a history of pulmonary embolism who presented in shock with ST-elevation on his electrocardiogram. He was triaged to the catheterization laboratory where he arrested. A pulmonary embolism was diagnosed angiographically, the thrombus was aspirated, and he received systemic thrombolysis. The combination of clot debulking and systemic thrombolysis acted synergistically to improve his right ventricular function by resolving his pulmonary hypertension. Although it is associated with a higher bleeding risk, the combination of clot aspiration with thrombolytic in the treatment of...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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