Modification Of Bile Acid Homeostasis By Iron Overload In Rats

Background and Aims: Excessive accumulation of iron (IO) in the liver accompany metabolic diseases associated with increased cholesterol plasma concentrations such as type II diabetes mellitus, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). Bile acids (BA) are important endogenous metabolic regulators that modulate these pathologies but mutual relationship of IO and BA turnover is not thoroughly studied. The aim of present study was to describe effect of IO on BA homeostasis in rats.
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Posters 26 - 29 May, 2019 Source Type: research