Modification Of Bile Acid Homeostasis By Iron Overload In Rats
Background and Aims: Excessive accumulation of iron (IO) in the liver accompany metabolic diseases associated with increased cholesterol plasma concentrations such as type II diabetes mellitus, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). Bile acids (BA) are important endogenous metabolic regulators that modulate these pathologies but mutual relationship of IO and BA turnover is not thoroughly studied. The aim of present study was to describe effect of IO on BA homeostasis in rats.
Source: Atherosclerosis - Category: Cardiology Authors: A. Pra šnická, H. Lastuvkova, J. Cermanova, M. Hroch, J. Mokry, E. Dolezelova, F. Alaei Faradonbeh, K. Zizalova, L. Vitek, P. Nachtigal, S. Micuda Tags: Posters 26 - 29 May, 2019 Source Type: research
More News: Bile | Cardiology | Cholesterol | Diabetes | Diabetes Mellitus | Endocrinology | Fatty Liver Disease (FLD) | Iron | Liver | Liver Disease | Metabolic Syndrome | Non-alcoholic Fatty Liver Diseases (NAFLD) | Study | Urology & Nephrology