Ultrasound- Guided Sono- Photomechanic Combination Therapy Of Abdominal Aorta Atherothrombosis Accompanied By Simultaneously Plga- Based Encapsulated Tpa Nanoparticles And Pesda Microbubbles Administration

Background and Aims: A plaque may rupture with high risk of subsequent thrombus mediated acute clinical events such as myocardial infarction and stroke. The aim of this study was to generate a hamster model of abdominal aorta atherothrombotic stenosis and the subsequent investigating the feasibility of sono- photomechanic combination thrombolytic therapy accompanied by simultaneously PLGA- based encapsulated tPA nanoparticles and microbubbles administration in this model.
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Posters 26 - 29 May, 2019 Source Type: research