Knowledge, attitudes and practices regarding tuberculosis among transgender individuals in the city of São Paulo, Brazil
Resumo O objetivo do estudo foi avaliar o conhecimento, as atitudes e as pr áticas em relação à tuberculose (TB), entre travestis e mulheres transexuais (trans). Trata-se de estudo transversal com amostra por conveniência (n = 124; 58 travestis e 66 trans) realizado na cidade de São Paulo em 2014, com a aplicação do Knowledge, attitudes and practices questionnaire ( KAP) adaptado. Calcularam-se as frequências absolutas e relativas para o conjunto das entrevistadas e as comparações entre as distribuições percentuais dos grupos foram realizadas pelo teste Qui-quadrado de Pearson, teste exato de Fisher ou sua generalização, com nível de significância de 5 %. A maioria era jovem e não branca. As travestis apresentaram menor escolaridade, referiram mais a passagem pelo sistema prisional e se autodeclararam trabalhadoras do sexo com maior frequência. Pouco mais da metade das entrevistadas tinha conhecimento sobre a gratuidade do tratamento. Neste estu do, o conhecimento sobre a TB mostrou-se modesto, permeado por equívocos associados aos sinais/sintomas e formas transmissíveis e preventivas da doença, que influenciam em suas atitudes e práticas em relação à doença. Os resultados sugerem que as ações de educação em saúde não têm ati ngido seus objetivos ...
We report the case of a male patient with cutaneous metastasis of prostate adenocarcinoma located in the cervical and upper thoracic area. The patient also had a history of pulmonary tuberculosis. A CT scan revealed the presence of bone metastasis, pleural effusion, and infiltration of the soft tissues of the neck. The histopathological study confirmed the presence of cutaneous metastasis of primary prostate neoplasia. We present this case due to its unusualness and its importance in the differential diagnosis of this pathology. PMID: 31800950 [PubMed - in process]
Conclusion: It was found that the majority of POEs containing a bioreducible center showed higher inhibitory activities on Mtb growth when compared to the similar compounds without a bio-reducible functional group. PMID: 31799156 [PubMed]
Conclusion: Multiplex PCR using MPB 64 and IS6110 primers has a high sensitivity and specificity in diagnosis of FGTB. PMID: 31801325 [PubMed - in process]
In this study, performance of a new experimental test based on the P22 protein complex (P22 ELISA) was evaluated in two TB-infected herds using milk and serum samples and compared with cell-based diagnostic tests. Samples from a low (n = 62, herd 1) and a high (n = 52, herd 2) TB prevalence herd were selected. Moreover, bulk tank milk samples from both herds were analysed using the P22 ELISA. At the end of the study, a group of animals (n = 21) was euthanized and subjected to post-mortem analysis and bacteriological culture. Significant differences (p
Authors: Bobak CA, McDonnell L, Nemesure MD, Lin J, Hill JE Abstract The growth of publicly available repositories, such as the Gene Expression Omnibus, has allowed researchers to conduct meta-analysis of gene expression data across distinct cohorts. In this work, we assess eight imputation methods for their ability to impute gene expression data when values are missing across an entire cohort of Tuberculosis (TB) patients. We investigate how varying proportions of missing data (across 10%, 20%, and 30% of patient samples) influence the imputation results, and test for significantly differentially expressed genes a...
This article has been withdrawn by the authors. Lanes 2–4 of Fig. 4A were reused in Fig. 5C. Lanes 1 and 2 of Fig. 4B were reused as lanes 2 and 3 of Fig. 7B. Lanes 5 and 6 of Fig. 4C were reused in Fig. 5D. Lanes 1 and 2 of Fig. 5A were reused in Fig. 5B. The authors state that several gels were run for each experiment and that the images were cropped to create panels. They further state that the wrong panels were selected while assembling the figures as they appeared very similar. The authors assert that these errors do not change the results of this article.
Publication date: Available online 29 November 2019Source: Journal of Molecular StructureAuthor(s): B.N. Ravi, Keshavayya J, Mallikarjuna N. M, Vinod Kumar, Shivanand KandgalAbstractAzo molecules (A1-A3) were prepared by reacting 2-aminothiazole with three different pyridone derivatives as coupling components, viz., 6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile, 6-hydroxy-1,4-dimethyl-2-oxo-1,2-dihydropyridine-3-nitrile and 1-ethyl-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile via diazo-coupling reactions, under appropriate experimental conditions. The structural characteristics of the synthesiz...
Condition: Pulmonary Tuberculosis Interventions: Drug: Moxifloxacin, Isoniazid, Rifampicin; Drug: Rifampicin,Isoniazid,Pyrazinamide,Ethambutol Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University Not yet recruiting
Condition: Tuberculosis Intervention: Other: INSTEP2 intervention package Sponsors: Universitas Padjadjaran; University of Otago; Harvard University Not yet recruiting