Inflammation is associated with pro ‐nociceptive brain connections in rheumatoid arthritis patients with concomitant fibromyalgia

ConclusionHere we provide the first neurobiological evidence that comorbid FM in RA may be linked to peripheral inflammation through pro ‐nociceptive patterns of brain connectivity. In patients with such ‘bottom‐up' pain centralization, comorbid symptoms may partially respond to anti‐inflammatory treatments.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - August 4, 2019 Category: Rheumatology Authors: Chelsea M. Kaplan, Andrew Schrepf, Eric Ichesco, Tony Larkin, Steven E. Harte, Richard E. Harris, Alison D. Murray, Gordon D. Waiter, Daniel J. Clauw, Neil Basu Tags: Brief Report Source Type: research