Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study

ConclusionLDCT with tin filtration and third-generation IR was applicable in evaluating ILD lesions of CTD. Image quality was significantly improved after applying ADMIRE algorithm to CT protocols.Key Points•Optimization of CT radiation dose is a clinical concern in patients with connective tissue disease.•Spectral shaping and third-generation iterative reconstruction emerge as promising techniques in reducing radiation dose and acquiring desired image quality of CTD-ILD patients.•The third-generation iterative reconstruction algorithm can optimize visualization of ILD patterns in low-dose CT.

Source: European Radiology - August 5, 2019 Category: Radiology Source Type: research