Translator was diagnosed with stage-four cancer after she dismissed her cough as 'part of winter' 

Magdalena Bujalski, 22, of Winnipeg, Canada, was told her cough was likely just bronchitis, until an X-ray revealed an unusual mass on her right lung. She was diagnosed with Non-Hodgkin Lymphoma.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Luminex can be added to the list of companies that have received Emergency Use Authorization (EUA) for a diagnostic to address the coronavirus (COVID-19) pandemic. The Austin, TX-based firm was granted the designation for the Aries SARS-CoV-2 Assay for the rapid detection of the virus that causes COVID-19. The assay runs on the Aries System, which is cleared by FDA and has the capability of running up to 144 tests per day. Recently Luminex received another EUA in addition to Medical Device Authorization for importation or sale for Health Canada for the NxTAG CoV Extended Panel. The company said the panel is a h...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news
Nadia, the tiger who tested positive for the novel coronavirus in New York, and six other big cats who developed a dry cough at the Bronx Zoo appeared to be on the mend on Monday after doses of medication and tenderness.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
BOSTON (CBS) — Researchers at Harvard University and Massachusetts General Hospital need your help to battle coronavirus, and this time it has nothing to do with social distancing or personal protection equipment (PPE). They are trying to recruit as many people as possible to download the COVID-19 Symptom Tracker app onto their smartphone and then tell them how they feel. “We need everyone to participate, whether well or sick, whether they feel they are risk or not,” explained Dr. Andrew Chan of Massachusetts General Hospital. The app was created in the U.K., and researchers there have already collected d...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Coronavirus Health News MGH Research Source Type: news
It is estimated that the three private clinic networks - Rutherford Health, Genesis Care and HCA UK - could treat an estimated 5,000 patients per month.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 6 April 2020Source: Journal of Molecular StructureAuthor(s): Saravanan Kandasamy, Prabhu Subramani, Selvi Subramani, John marshal Jayaraj, Gunasekaran Prasanth, Kannupal Srinivasan, Karthikeyan Muthusamy, Venkatachalam Rajakannan, Ravikumar Vilwanathan
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Manufacturing giant 3M says it has an agreement with the Trump administration that will allow the company to continue to export N95 protective masks to Canada and Latin America amid the coronavirus pandemic
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
m M Abstract The cytokine tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the large TNF superfamily that can trigger apoptosis in transformed or infected cells by binding and activating two receptors, TRAIL receptor 1 (TRAILR1) and TRAIL receptor 2 (TRAILR2). Compared to other death ligands of the same family, TRAIL induces apoptosis preferentially in malignant cells while sparing normal tissue and has therefore been extensively investigated for its suitability as an anti-cancer agent. Recently, it was noticed that TRAIL receptor signaling is also linked to endoplasmic reticulu...
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Tags: Int Rev Cell Mol Biol Source Type: research
Mcl-1 as a "barrier" in cancer treatment: Can we target it now? Int Rev Cell Mol Biol. 2020;351:23-55 Authors: Pervushin NV, Senichkin VV, Zhivotovsky B, Kopeina GS Abstract During the last two decades, the study of Mcl-1, an anti-apoptotic member of the Bcl-2 family, attracted researchers due to its important role in cancer cell survival and tumor development. The significance of Mcl-1 protein in resistance to chemotherapeutics makes it an attractive target in cancer therapy. Here, we discuss the diverse possibilities for indirect Mcl-1 inhibition through its downregulation, for example, vi...
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Tags: Int Rev Cell Mol Biol Source Type: research
Abstract Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs), intracellular calcium (Ca2+) release channels, fulfill key functions in cell death and survival processes, whose dysregulation contributes to oncogenesis. This is essentially due to the presence of IP3Rs in microdomains of the endoplasmic reticulum (ER) in close proximity to the mitochondria. As such, IP3Rs enable efficient Ca2+ transfers from the ER to the mitochondria, thus regulating metabolism and cell fate. This review focuses on one of the three IP3R isoforms, the type 3 IP3R (IP3R3), which is linked to proapoptotic ER-mitochondrial Ca2+ transfer...
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Tags: Int Rev Cell Mol Biol Source Type: research
Abstract Apoptosis is an important part of both health and disease and is often regulated by the BCL-2 family of proteins. These proteins are either pro- or anti-apoptotic, existing in a delicate balance during homeostasis. They are best known for their role in regulating the activation of caspases and the execution of a cell in response to a variety of stimuli. However, it is often forgotten that these BCL-2 family proteins also have important roles to play in cell maintenance that are not associated with apoptosis. These include roles in regulating processes such as cell cycle progression, mitochondrial function...
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Tags: Int Rev Cell Mol Biol Source Type: research
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