Psychosocial Interventions for Young Adults With Hip Pain

Conditions:   Hip Dysplasia;   Hip Pain Chronic;   Hip Osteoarthritis;   Hip Arthritis;   Psychosocial Problem Interventions:   Device: Cell Phone Based Cognitive Based Therapy (Pacifica App);   Other: Control Sponsor:   Michael C Willey Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Conditions:   Chronic Pain;   Fibromyalgia;   Osteoarthritis, Knee;   Osteoarthritis, Hip;   Osteoarthritis;   Ankylosing Spondylitis;   Rheumatoid Arthritis;   Chronic Low-back Pain;   Chronic Shoulder Pain Intervention:   Other: No intervention, observational only. Sponsor:   Illinois Institute of Technology Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractRheumatoid arthritis (RA) is a systemic, autoimmune disease that affects joints and extra-articular structures. In the last decade, the management of this chronic disease has dramatically changed with the introduction of several targeted mechanisms of action, such as tumor necrosis factor- α inhibition, T-cell costimulation inhibition, B-cell depletion, interleukin-6 blockade, and Janus kinase inhibition. Beyond its well-known hematopoietic role on the proliferation and differentiation of myeloid cells, granulocyte-monocyte colony-stimulating factor (GM-CSF) is a proinflammatory medi ator acting as a cytokine...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
Conclusions: Genicular nerve ablation with radiofrequency has demonstrated favorable outcomes with low complication rates.
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Review Article Source Type: research
This study explored the role of central sensitization (CS) pain in patients with various rheumatic diseases using the CS inventory (CSI).MethodsA total of 193 patients of mean age 50.72  ± 9.65 years were included; they were divided into four different groups in terms of their rheumatic diseases. Patients with rheumatoid arthritis (RA), spondyloarthropathy (SpA), osteoarthritis (OA), and fibromyalgia syndrome (FMS) were evaluated in tertiary care rheumatology/pain medicine se ttings. Disease duration and activity, the Bath Ankylosing Spondylitis Disease Activity Index, the Disease Activity Score-2...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
In conclusion, with study of the frailty syndrome still in its infancy, frailty analysis remains a major challenge. It is a challenge that needs to be overcome in order to shed light on the multiple mechanisms involved in the pathogenesis of this syndrome. Although several mechanisms contribute to frailty, immune system alteration seems to play a central role: this syndrome is characterized by increased levels of pro-inflammatory markers and the resulting pro-inflammatory status can have negative effects on various organs. Future studies should aim to better clarify the immune system alteration in frailty, and seek to esta...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsMore than half of Medicaid beneficiaries receiving an opioid for pain management do so for orthopedic- and dental-related reasons, with emergency department providers more likely to prescribe opioids. Modifications to the guidelines addressing temporary acute pain management practices with opioids would be likely to benefit emergency department providers the most.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
In this study, UBX0101 was well-tolerated. Improvement in several clinical outcomes, including pain and function, as well as modulation of certain senescence-associated secretory phenotype (SASP) factors and disease-related biomarkers was observed after a single dose of UBX0101. UNITY plans to initiate a Phase 2 study of UBX0101 in patients with painful, moderate-to-severe OA of the knee. The study is expected to enroll approximately 180 patients with initiation expected in the fourth quarter of 2019 and initial 12-week results expected in the second half of 2020. This will be a randomized, double-blind, placebo-con...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Conclusions: Ochronosis is a very rare disease in Asia. This paper supplies new information for study of this disease. The mechanism is still unknown right now. Further studies will be necessary.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Conditions:   Hip Dysplasia;   Hip Pain Chronic;   Hip Osteoarthritis;   Hip Arthritis;   Psychosocial Problem Interventions:   Device: Cell Phone Based Cognitive Based Therapy (Pacifica App);   Other: Control Sponsor:   Michael C Willey Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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