Diagnostics and treatment of preoperative anemia.

[Diagnostics and treatment of preoperative anemia]. Anaesthesist. 2019 Aug 01;: Authors: Rosenthal C, von Heymann C, Kaufner L Abstract Approximately 14-40% of patients in industrialized countries present with preoperative anemia. Depending on the severity, anemia is associates with increased perioperative morbidity and mortality. One of the most important causes of preoperative anemia is iron deficiency which is usually easy to treat. Implemented in the multimodal concept of patient blood management, the diagnostics and treatment of preoperative anemia are important aspects for improvement of perioperative outcome. Adequate and early diagnostics of the cause of anemia before treatment is important because treatment options, e.g. with iron, erythropoetin, folic acid and vitamin B12, may be expensive, may have severe side effects, and in the case of a wrong indication, will not improve anemia. In addition, an adequate regeneration of the erythrocyte volume requires time. This review article presents important aspects of the epidemiology and prognostic implications of preoperative anemia, the physiology and pathophysiology of anemia as well as diagnostic features and the evidence base for preoperative treatment options. PMID: 31372673 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research

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Vitamin B12 deficiency has a storied history including 2 Nobel Prizes, beginning with the discovery of an anemia by the English physician and scientist Thomas Addison in the 1840s. In the preface to his treatise on adrenal insufficiency (Addison disease), he described a  single case of what was termed “Addisonian anemia.”1 German physician Michael Biermer working in Zurich, more convincingly described what he termed “progressive pernicious anemia” in the 1870s, reporting 15 cases in great detail.
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Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
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Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
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