Cutting Off Leukemogenesis: Hydra-like Plasticity of Mature Leukemic Cells.

Cutting Off Leukemogenesis: Hydra-like Plasticity of Mature Leukemic Cells. Cell Stem Cell. 2019 Aug 01;25(2):167-168 Authors: Bamezai S, Buske C Abstract Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) can drive tumor growth and relapse. In this issue of Cell Stem Cell, McKenzie et al. (2019) report that some mature leukemic cells can de-differentiate and contribute to AML tumorigenesis, a finding with important implications for therapies focused on eradicating LSCs. PMID: 31374194 [PubMed - in process]
Source: Cell Stem Cell - Category: Stem Cells Authors: Tags: Cell Stem Cell Source Type: research