Normal Values of T, B and NK Lymphocyte Subpopulations in Peripheral Blood of Healthy Cuban Adults.

Normal Values of T, B and NK Lymphocyte Subpopulations in Peripheral Blood of Healthy Cuban Adults. MEDICC Rev. 2019 Apr-Jul;21(2-3):16-21 Authors: Kokuina E, Breff-Fonseca MC, Villegas-Valverde CA, Mora-Díaz I Abstract INTRODUCTION Quantification of lymphocyte subpopulations is useful for evaluating immune response in states of health and disease, including immunodeficiencies, autoimmunity, infections and cancer. Studies have found that concentrations and proportions of different cell subpopulations vary with geographic location, age, sex and ethnicity. Knowing the normal values of these cells and their variation in healthy populations will contribute to improved clinical practice and scientific research. OBJECTIVE Estimate normal absolute concentrations and percentages of the most abundant lymphocyte subpopulations in peripheral blood and their relation to sex and age. METHODS A cross-sectional analysis was conducted in 129 healthy adults, 61 men and 68 women aged 18-80 years; 89 aged
Source: MEDICC Review - Category: International Medicine & Public Health Tags: MEDICC Rev Source Type: research

Related Links:

ConclusionWe believe that these efforts will help to significantly improve the gastrointestinal cancer treatment and survival.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
AbstractIndividuals at high risk for pancreatic cancer are recommended surveillance and healthy lifestyle behaviours and patient experience with recommendations are understudied. To describe engagement and experience with surveillance, tobacco and alcohol use, health beliefs and motivation (Champion Health Belief Measure) and the relationship with personal, psychosocial (Impact of Event Scale), and familial characteristics. Interest in integrative therapies (complementary therapies) are described. A multi-site cross-sectional survey including individuals at high risk for pancreatic cancer with no diagnosis of pancreatic ca...
Source: Familial Cancer - Category: Cancer & Oncology Source Type: research
tto M Abstract INTRODUCTION: the goal of this study was to evaluate if there is an association between dietary components related to inflammation processes and oral squamous cell carcinoma (OSCC) in Argentina. METHODS: case-control study 3:1, both genders, ages 24-80 years attended at External Offices of Facultad Odontología Universidad Nacional de Córdoba between 2012 and 2015. Dietary information was collected using a qualitative-quantitative food frequency questionnaire. The Dietary Inflammatory Index (DII) was applied. Logistic regression was applied in order to assess the association among ...
Source: Nutricion Hospitalaria - Category: Nutrition Authors: Tags: Nutr Hosp Source Type: research
Abstract Macroautophagy/autophagy can enable cancer cells to withstand cellular stress and maintain bioenergetic homeostasis by sequestering cellular components into newly formed double-membrane vesicles destined for lysosomal degradation, potentially affecting the efficacy of anti-cancer treatments. Using 13C-labeled choline and 13C-magnetic resonance spectroscopy and western blotting, we show increased de novo choline phospholipid (ChoPL) production and activation of PCYT1A (phosphate cytidylyltransferase 1, choline, alpha), the rate-limiting enzyme of phosphatidylcholine (PtdCho) synthesis, during autophagy. We...
Source: Autophagy - Category: Cytology Authors: Tags: Autophagy Source Type: research
CONCLUSION: 7.5% of HCC presented without cirrhosis and almost half of patients had mild fibrosis. HBV was the main cause of HCC, followed by NASH. The most frequent BCLC stage at diagnosis was early stage and surgery was the most common treatment. Overall cumulative survival at 5 years was almost 50%. PMID: 31497990 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Conclusion.Prophylactic use of steroid‐containing oral rinses can prevent/ameliorate mIAS in patients with MBC treated with AIE. MMW + hydrocortisone is an affordable option, as is dexamethasone oral rinse.Implications for Practice.This prospective phase‐II study showed that two steroid‐containing mouthrinses substantially reduced incidences of all‐grade and grade ≥2 stomatitis and related oral adverse events (AEs), and the number of everolimus dose‐delays and/or dose‐reduction in metastatic breast cancer (MBC) patients receiving everolimus treatment plus an aromatase inhibitor. Both ora...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Symptom Management and Supportive Care, Breast Cancer Source Type: research
The liver contains both NK cells and their less cytotoxic relatives, ILC1. Here, we investigate the role of NK cells and ILC1 in the obesity-associated condition, non-alcoholic fatty liver disease (NAFLD). In the livers of mice suffering from NAFLD, NK cells are less able to degranulate, express lower levels of perforin and are less able to kill cancerous target cells than those from healthy animals. This is associated with a decreased ability to kill cancer cells in vivo. On the other hand, we find that perforin-deficient mice suffer from less severe NAFLD, suggesting that this reduction in NK cell cytotoxicity may be pro...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
By Wan Manan Muda and Jomo Kwame SundaramKUALA LUMPUR, Malaysia, Sep 10 2019 (IPS) Smoking-related diseases are the major causes of premature death worldwide. Every year, six million smoking-related deaths are reported worldwide. If current smoking trends persist, 8 million deaths can be expected by 2030, of which four-fifths will occur in lower- and middle-income countries. Start them young Many studies show that smoking is typically learned and started during adolescence. Owing to nicotine addiction, the earlier someone starts to smoke, the higher the likelihood he or she will continue the habit into adulthood, and the ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Featured Global Headlines Health TerraViva United Nations Source Type: news
baş CS, Açıcı M Abstract A 25-year-old male patient, who had terminal stage skin cancer (malignant melanocytic neoplasia) on his skin of arm was infected with white, round, worm parasites in the lesion area of the skin. Parasites were collected with a thin forceps in a petri dish, cleaned in warm physiological saline, fixed by 70% hot ethyl alcohol and clarified in lactophenol, respectively. All 14 female and 7 male nematodes, some of which had partial autolysis, were identified as Ascaridia galli, a chicken nematode. Due to the fact that it is a very rare case in the medical literature, we wish to repor...
Source: Turkish Society for Parasitology - Category: Parasitology Authors: Tags: Turkiye Parazitol Derg Source Type: research
CONCLUSIONS: Compared with animal species, no human-specific metabolite was found in HLM. And dog had closer metabolic profile to humans. This study would be helpful for us to understand the species difference in pharmacokinetics/pharmacodynamics. KEWORDS: olaparib, metabolite characterization, liver microsomes, interspecies comparison. PMID: 31499579 [PubMed - as supplied by publisher]
Source: Rapid Communications in Mass Spectrometry : RCM - Category: Chemistry Authors: Tags: Rapid Commun Mass Spectrom Source Type: research
More News: Alcoholism | Cancer | Cancer & Oncology | Cuba Health | International Medicine & Public Health | Smokers | Study | Women