Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry.

CONCLUSION: Analysis of long-term data from this prospective real-world registry demonstrated a safety profile consistent with previous studies in patients with RA. This analysis did not identify any new safety signals associated with adalimumab treatment and provides valuable guidance for physicians prescribing adalimumab for extended periods of time. PMID: 31371657 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research

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Publication date: Available online 12 September 2019Source: Revista Portuguesa de Cardiologia (English Edition)Author(s): Sofia Torres, Sandra Amorim, Mariana Vasconcelos, Carla Sousa, M. Júlia Maciel, Filipe Macedo
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Conclusion: Our data provide evidence that homing of breast cancer cells is independent of their ER status and that the breast cancer bone metastasis niche is located within the trabecular region of bone, an area rich in osteoblasts and microvessels. The increased number of breast cancer cells homing to bone after mobilisation of HSCs suggests that the HSC and the bone metastasis niche overlap.
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
Date: Thursday, 10 31, 2019; Speaker: Angelika Amon, Ph.D., Professor of Biology , Massachusetts Institute of Technology; Building: Building 50; Room 1227/1233
Source: NIH Calendar of Events - Category: American Health Source Type: events
Conclusions: The predictability of the Blue Cross models show how member-specific, regional data can be used to accurately identify patients with a high ROH, which may allow healthcare workers to intervene earlier and subsequently reduce the healthcare burden for patients and providers. PMID: 31505982 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
Conclusions The swab home collection samples were equivalent to the clinical samples, but the tampon method had an unacceptably high rate of specimens insufficient for HPV detection.
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Studies Source Type: research
Authors: Marra G, Dell'oglio P, Baghdadi M, Cathelineau X, Sanchez-Salas R, EvaluatioN of HIFU Hemiablation and short term AndrogeN deprivation therapy Combination to Enhance prostate cancer control (ENHANCE) study investigators Abstract FT for localized PCa is emerging to reduce adverse effects of radical treatments, while maintaining comparable oncological outcomes. However, an area for improvement still exists and a gap in cancer control needs to be filled by complementing the with additional forms of treatment to minimize failures. Part of the recurrences/persistences after FT may be related to PCa microenviron...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
In this study, a series of anthropomorphic software breast phantoms (ASBPs) with various volumes and glandularities were built. The realism of the ASBPs was assessed by using the two-dimensional projection and fractal dimension (FD) analysis. Breast self S values and suborgan S values for 18F and 99mTc were simulated using the Monte Carlo technique. The projected images of the ASBPs were similar to clinical mammograms in tissue distribution and image contrast. The mean FD value for the ASBPs was 2.23. The maximum differences between the breast self S values of ASBPs and OLINDA/EXM for 18F and 99mTc were −14.4% and &m...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Contributors : P Sharma ; W E Barlow ; A K Godwin ; E E Parkes ; L A Knight ; S M Walker ; R D Kennedy ; D P Harkin ; G E Logan ; C J Steele ; S M Lambe ; S Badve ; Y Gokmen-Polar ; H B Pathak ; K Isakova ; H M Linden ; P Porter ; L Pusztai ; A M Thompson ; D Tripathy ; G N Hortobagyi ; D F HayesSeries Type : Expression profiling by arrayOrganism : Homo sapiensPurpose: The purpose of this study was to independently validate two biomarkers, a 44-gene DNA Damage Immune Response (DDIR) signature and stromal tumor-infiltrating lymphocytes (sTILs), as prognostic markers in TNBC patients treated with adjuvant doxorubicin (A) and...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Contributors : Purnima Gupta ; Naveed Shahzad ; Alexis Robitaille ; Hector Hernandez-Vargas ; Geoffroy Durand ; Florence Le Calvez-Kelm ; Tarik Gheit ; Rosita Accardi ; Massimo TommasinoSeries Type : Expression profiling by arrayOrganism : Homo sapiensMerkel cell polyomavirus (MCPyV) is the first human polyomavirus etiologically associated with Merkel cell carcinoma (MCC), a rare and aggressive form of skin cancer. Similar to other polyomaviruses, MCPyV encodes early T antigen genes, a viral oncogene required for MCC tumor growth. To identify the unique oncogenic properties of MCPyV, we analysed the gene expression profile...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
We reported the gene expression profiles of 9 human colon cancer samples and their matching adjacent normal tissues.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
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