Analysis of nickel distribution by synchrotron radiation X-ray fluorescence in nickel-induced early- and late-phase allergic contact dermatitis in Hartley guinea pigs.

CONCLUSIONS: This study showed that the distribution of the nickel element concentration in ACD skin tissue was different between the early phase and late phase groups. The nickel element was not present in the Ni aqueous ionic state but bound with certain proteins to form a complex in the stratum corneum in ACD model tissue.
PMID: 31373908 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - July 31, 2019 Category: General Medicine Authors: Jiang SQ, Wu XY, Sun JL, Chen G, Tang R, Li Z, Wei RY, Liang L, Zhou XJ, Chen DL, Li J, Gao H, Zhang J, Zhao ZT Tags: Chin Med J (Engl) Source Type: research