Perturbations of urea cycle enzymes during post-hepatectomy rat liver failure.

Conclusion:At the protein level, we found perturbations of urea cycle and related enzymes in the MSFLR during PHLF. Our results suggest that these perturbations may augment urea cycle function which may be pivotal for increased ammonia elimination after extensive PHs and potential PHLF.
PMID: 31373508 [PubMed - as supplied by publisher]

Source: Am J Physiol Gastroi... - August 1, 2019 Category: Gastroenterology Authors: Meier M, Knudsen AR, Andersen KJ, Ludvigsen M, Lykke Eriksen P, Pedersen AKN, Honoré B, Mortensen FV Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research