Combined brain/heart magnetic resonance imaging in systemic lupus erythematosus.
Combined brain/heart magnetic resonance imaging in systemic lupus erythematosus. Curr Cardiol Rev. 2019 Aug 01;: Authors: Mavrogeni S, Koutsogeorgopoulou L, Dimitroulas T, Markousis-Mavrogenis G, Boki K, Katsifis G, Vartela V, Kallenberg CG, Kolovou G, Kitas G Abstract Cardiovascular disease (CVD) in systemic lupus erythematosus (SLE) and neuropsychiatric SLE (NPSLE) have an estimated prevalence of 50% and 40% respectively and both constitute major causes death among SLE patients. In this review, we propose a combined brain/heart magnetic resonance imaging (MRI) for SLE risk stratification. The pathophysiologic background of NPSLE includes microangiopathy, macroscopic infarcts and accelerated atherosclerosis. Classic brain MRI findings demonstrate lesions suggestive of NPSLE in 50% of NPSLE cases, while advanced MRI indices can detect pre-clinical lesions in the majority of them, but their clinical impact still remains unknown. Cardiac involvement in SLE includes myo-pericarditis, valvular disease/endocarditis, heart failure (HF), coronary macro-micro-vascular disease, vasculitis and pulmonary hypertension. Classic and advanced cardiovascular magnetic resonance (CMR) indices allow function and tissue characterization for early diagnosis and treatment follow up of CVD in SLE. Although currently there are no clinical data supporting the combined use of brain/heart MRI in asymptomatic SLE, it may have a place in cases with clinical suspicion of brain/heart i...
This study compared stroke characteristics and poststroke care and disability between these groups.Stroke
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Those suffering from cancer, heart conditions, strokes, diabetes and lung disease are among the worst affected by delays to their diagnosis and care, a survey of senior doctors reveals.
CONCLUSION: Anti-NMO assays, made available during the last five years with the help of The Guthy-Jackson Charitable Foundation, have led to a clear jump in the number of cases diagnosed. Major advances in the field of epidemiology, imaging, and pathophysiology of NMO-SD have led to improved patient care and outcome. PMID: 32741562 [PubMed - as supplied by publisher]
HIGH blood pressure is a largely symptomless silent killer. If a person ignores their blood pressure because they think a certain symptom will alert them to the problem, they are taking a dangerous chance with their life. There are two waring signs which lay in a person's face.
Conclusions: Changing national guidelines with discard of contraindications for anticoagulation and the introduction of DOACs led to a broader recommendation of oral anticoagulation. However, both, new guidelines and DOACs, were not found to be associated with an increasing percentage of patients discharged from our hospital already on recommended anticoagulant prevention. This might be explained by the decreasing length of hospital stay during the study period and a missing evidence of early bleeding risk of DOACs in patients with acute brain infarction. Evidence-based data to close this therapeutic gap are needed.Cerebrovasc Dis
Conclusions: In our large cohort of CAS patients, coexistent UIAs are not uncommon. Stenting of a carotid artery in the presence of coexistent UIAs could be conducted safely. Together with 3-month dual antiplatelet therapy, CAS did not increase the rupture risk of the coexistent UIAs within 3 months.Cerebrovasc Dis
Publication date: Available online 3 August 2020Source: Stem Cell ResearchAuthor(s): Glen Lester Sequiera, Cheryl Rockman-Greenberg, Sanjiv Dhingra
This report demonstrates the detailed clinico-investigative profile of a child who survived rabies following inadequate post-exposure prophylaxis and adds to the sparse knowledge of this usually fatal condition. ABBREVIATIONS: ADEM, acute disseminated encephalomyelitis; CBNAAT, cartridge-based nucleic acid amplification test; CSF, cerebrospinal fluid; EEG, electroencephalogram; GCS, Glasgow coma scale; EVM, eye opening, best verbal response, best motor response; IM, intramuscular; IVIg, intravenous immunoglobulin; MRC, Medical Research Council; MRI/FLAIR, magnetic resonance imaging/fluid attenuation inversion recovery;...
CONCLUSION: The studies confirmed the effectiveness of various forms of VR treatment in the alleviation of psychological and behavioral problems and psychiatric disorders. There is a shortage of VR-based technological solutions that would, besides physical rehabilitation, offer stroke patients therapeutic tools to alleviate psychological disturbance and improve the patient's mood and motivation. Such solutions will most likely become a field of intensive research in the coming years. PMID: 32741792 [PubMed - as supplied by publisher]