Combined brain/heart magnetic resonance imaging in systemic lupus erythematosus.

Combined brain/heart magnetic resonance imaging in systemic lupus erythematosus. Curr Cardiol Rev. 2019 Aug 01;: Authors: Mavrogeni S, Koutsogeorgopoulou L, Dimitroulas T, Markousis-Mavrogenis G, Boki K, Katsifis G, Vartela V, Kallenberg CG, Kolovou G, Kitas G Abstract Cardiovascular disease (CVD) in systemic lupus erythematosus (SLE) and neuropsychiatric SLE (NPSLE) have an estimated prevalence of 50% and 40% respectively and both constitute major causes death among SLE patients. In this review, we propose a combined brain/heart magnetic resonance imaging (MRI) for SLE risk stratification. The pathophysiologic background of NPSLE includes microangiopathy, macroscopic infarcts and accelerated atherosclerosis. Classic brain MRI findings demonstrate lesions suggestive of NPSLE in 50% of NPSLE cases, while advanced MRI indices can detect pre-clinical lesions in the majority of them, but their clinical impact still remains unknown. Cardiac involvement in SLE includes myo-pericarditis, valvular disease/endocarditis, heart failure (HF), coronary macro-micro-vascular disease, vasculitis and pulmonary hypertension. Classic and advanced cardiovascular magnetic resonance (CMR) indices allow function and tissue characterization for early diagnosis and treatment follow up of CVD in SLE. Although currently there are no clinical data supporting the combined use of brain/heart MRI in asymptomatic SLE, it may have a place in cases with clinical suspicion of brain/heart i...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research

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Publication date: Available online 15 November 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): L. May, J. Blatter, P. Bize, G. Tsoumakidou, A. Denys, M. BroomeAbstractTreatment of bony tumours of the oral and maxillofacial area usually involve resection. However, access to certain areas may be difficult because of the size or site of the tumour. A poor view of the lesion during operation is another limiting factor, which can lead to incomplete resection in difficult cases. Percutaneous cryoablation is a common procedure for treating benign and malignant bony lesions outside the oral and maxillofacia...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
ConclusionAccording to the results, whey supplementation significantly reduced the SBP, DBP, HDL, waist circumference, TG and FBS in intervention groups in comparing to control groups.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSION: The various evaluation methods for predicting a pCR after PCRT show a predictive sensitivity of 0.15-0.41 for primary tumors and 0.52-0.88 for lymph nodes. Endoscopy is a relatively superior modality for predicting the pCR of the primary tumor of LARC patients. PMID: 31726004 [PubMed]
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
ConclusionCo-administration of Rg3-KRG+AG is an effective add-on for improving BP along with attaining favorable cardiometabolic outcomes in individuals with type 2 diabetes. Ginseng derivatives may offer clinical utility when included in the polypharmacy and lifestyle treatment of diabetes.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Publication date: February 2020Source: IJC Heart &Vasculature, Volume 26Author(s): Alexander C. Egbe, Keerthana Banala, Rahul Vojjini, Karim Osman, Arslan Afzal, Vaibhav Jain, Sahith Thotamgari, Naser M. AmmashAbstractCardiac magnetic resonance imaging derived right ventricular (RV) volumes are often necessary for optimal timing of pulmonary valve replacement in patients with tetralogy of Fallot (TOF). This practice is based on previous studies that reported preoperative RV volumetric thresholds that predicted postoperative RV remodeling. As a result, pulmonary valve replacements are being performed even in asymptomati...
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
ConclusionsOPTM of SERCA2 correlate with myocardial fibrosis in NICM. In younger patients, OPTM of SERCA2 correlate with elevated BNP and increased composite MACE.
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
Atrial fibrillation (AF) is the most common arrhythmia and poses a substantial economic burden due to associated thromboembolic complications. Screening for AF may theoretically be effective, but there is no consensus regarding the optimal screening method because the available tools are either invasive or not cost-effective. Recently, smartwatch industry has received a surge of interest for this purpose by introducing technologies such as photoplethysmography, artificial intelligence, and actual electrodes taking an electrocardiogram to measure and analyze heart rate and rhythm with relatively acceptable accuracy. Combine...
Source: Critical Pathways in Cardiology - Category: Cardiology Tags: Review Article Source Type: research
Transthyretin amyloid deposition is present in 17% of autopsies of patients with heart failure and a preserved ejection fraction (HFpEF). 99mTechnetium-pyrophosphate scintigraphy (99mTc-PYP) is sensitive and specific to diagnose cardiac transthyretin amyloid deposition (ATTR). The prevalence of ATTR by 99mTc-PYP was evaluated along with echocardiographic parameters in patients with HFpEF. One-hundred consecutive patients with HFpEF, who had 99mTc-PYP, were retrospectively evaluated. Echocardiographic variables were analyzed to compare patients with positive versus negative ATTR infiltration. Myocardial ATTR was present in ...
Source: Critical Pathways in Cardiology - Category: Cardiology Tags: Original Articles Source Type: research
Publication date: January 2020Source: American Heart Journal, Volume 219Author(s): Benjamin D. Horne, Colleen A. Roberts, Kismet D. Rasmusson, Jason Buckway, Rami Alharethi, Jalisa Cruz, R. Scott Evans, James F. Lloyd, Tami L. Bair, Abdallah G. Kfoury, Donald L. LappéObjectiveUsing augmented intelligence clinical decision tools and a risk score-guided multidisciplinary team-based care process (MTCP), this study evaluated the MTCP for heart failure (HF) patients' 30-day readmission and 30-day mortality across 20 Intermountain Healthcare hospitals.BackgroundHF inpatient care and 30-day post-discharge management requir...
Source: American Heart Journal - Category: Cardiology Source Type: research
Interruption of oral anticoagulation, marijuana and stroke, ORBITA substudy, ISCHEMIA medical therapy targets, and more on AHA are the topics discussed by Dr. John Mandrola in this week ’ s podcast.theheart.org on Medscape
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology Commentary Source Type: news
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