The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor [RESEARCH ARTICLE]
This study definitively shows that the MMTV-Wnt1 mouse model produces two phenotypically distinct subtypes of mammary tumors that differ in multiple biological aspects including sensitivity to an EGFR inhibitor.
Source: DMM Disease Models and Mechanisms - Category: Biomedical Science Authors: Pfefferle, A. D., Darr, D. B., Calhoun, B. C., Mott, K. R., Rosen, J. M., Perou, C. M. Tags: Cancer RESEARCH ARTICLE Source Type: research
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