Unexpected detection of 3 ‐aroylbenzofuran side products in the preparation of 2‐arylbenzofurans: identification, characterization and comparison with chalcone's fragmentation patterns using EI/MSn

This study reports the identification of the by‐product,i.e. the 3 ‐benzoyl‐2‐phenylbenzofuran, on the base of its mass spectrometric behaviour using a combination of electron ionization (EI), exact mass measurement, multiple stage mass spectrometry and labelled compounds. This study reports the common fragmentation pathways and discusses possible fragment st ructures of characteristic ions from a series of 3‐aroyl‐2‐arylbenzofuran derivatives obtained as by‐product under Wittig conditions. Emphasis is laid on the formation and structure investigation of the [M‐H]+ and [M ‐OH]+ ions. Our results showed interesting analogies with the mass spectrometric behavior of chalcones.

Source: Journal of Mass Spectrometry - July 31, 2019 Category: Chemistry Authors: Michela Begala, Giovanna Lucia Delogu Tags: RESEARCH ARTICLE Source Type: research