Peripapillary Retinal Nerve Fibre Layer Thinning in Genetic Generalized Epilepsy
Genetic generalized epilepsy (GGE) comprises common epilepsies characterized by an electroclinical phenotype, complex genetic component and presumed common pathogenetic mechanism [1,2]. GGE shows no structural lesions on conventional MRI [2]. However, studies based on more advanced imaging technologies have shown subtle differences in brain structure [3 –6]. MRI volumetry and voxel-based morphometry studies have demonstrated regional changes, particularly thalamic volume loss, in GGE patients [4,7,8].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Jes ús González de la Aleja, Maripaz Guerrero-Molina, Rosa Ana Saíz-Díaz, Francisco López-Muñoz, Isidoro Raga-Martínez, Jesús Hernández-Gallego, Patricia Navarrete-Chamorro, Francisco Javier Povedano-Montero Source Type: research