Molecules, Vol. 24, Pages 2806: Application of Dithiocarbamates as Potential New Antitrypanosomatids-Drugs: Approach Chemistry, Functional and Biological

Molecules, Vol. 24, Pages 2806: Application of Dithiocarbamates as Potential New Antitrypanosomatids-Drugs: Approach Chemistry, Functional and Biological Molecules doi: 10.3390/molecules24152806 Authors: Johny Wysllas de Freitas Oliveira Hugo Alexandre Oliveira Rocha Wendy Marina Toscano Queiroz de Medeiros Marcelo Sousa Silva Dithiocarbamates represent a class of compounds that were evaluated in different biomedical applications because of their chemical versatility. For this reason, several pharmacological activities have already been attributed to these compounds, such as antiparasitic, antiviral, antifungal activities, among others. Therefore, compounds that are based on dithiocarbamates have been evaluated in different in vivo and in vitro models as potential new antimicrobials. Thus, the purpose of this review is to present the possibilities of using dithiocarbamate compounds as potential new antitrypanosomatids-drugs, which could be used for the pharmacological control of Chagas disease, leishmaniasis, and African trypanosomiasis.
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research