Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy.

Conclusions: PT reduced the volumes of normal tissues exposed to radiation, particularly low-to-intermediate dose levels, and this was reflected in lower NTCP. Of the included endpoints, substantial reductions in population medians were seen from the delivered PT plans for auditory complications, xerostomia, and risk of secondary cancers of the brain and salivary glands.
PMID: 31364899 [PubMed - as supplied by publisher]

Source: Acta Oncologica - July 30, 2019 Category: Cancer & Oncology Authors: Stokkevåg CH, Indelicato DJ, Herfarth K, Magelssen H, Evensen ME, Ugland M, Nordberg T, Nystad TA, Hægeland C, Alsaker MD, Ulven K, Dale JE, Engeseth GM, Boer CG, Toussaint L, Kornerup JS, Pettersen HES, Brydøy M, Brandal P, Muren LP Tags: Acta Oncol Source Type: research