Establishing an effective dose for chronic intracerebroventricular administration of clozapine in mice.

CONCLUSION: Our findings indicate that 7 mg/ml may be the optimal dose for chronic icv delivery of clozapine in mice, allowing comparison to screen for novel antipsychotic compounds. PMID: 31364522 [PubMed - as supplied by publisher]
Source: Acta Neuropsychiatrica - Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research