STE20/SPS1-related Proline/alanine-rich Kinase (SPAK) is Critical for Sodium Reabsorption in Isolated Perfused Thick Ascending Limb.

In conclusion, the combined net effect of SPAK isoforms on sodium reabsorption in TAL is stimulatory. SPAK is not essential for vasopressin stimulation of sodium reabsorption in TAL. PMID: 25477470 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25477470?dopt=Abstract

Source: Am J Physiol Renal P... - December 4, 2014 Category: Urology & Nephrology Authors: Cheng CJ, Yoon J, Baum M, Huang CL Tags: Am J Physiol Renal Physiol Source Type: research

More News: Sodium | Urology & Nephrology