Role of 18F-FDG PET/CT in the detection of primary malignancy in patients with bone metastasis of unknown origin

ConclusionsPET/CT, as a non-invasive method, can be preferred as the first choice in the detection of primary tumor in patients with BMUO.ResumenObjetivoEste trabajo analiza el papel de la PET/TC con 18F-FDG en la detección del tumor primario en pacientes con metástasis óseas de origen desconocido (MOOD).Material y MétodosEste estudio retrospectivo consideró al análisis histopatológico o el seguimiento clínico como datos de referencia en el diagnóstico de tumores primarios y estos resultados fueron comparados con los resultados de la PET/TC.ResultadosSe incluyeron 100 pacientes con MOOD (74 hombres, 26 mujeres; edad media de 61 años). El tumor primario se identificó en 92 de los 100 pacientes. El tipo histopatológico más común en los pacientes en los que se detectó el tumor primario fue el adenocarcinoma (65.2%). El tumor primario más frecuente fue el cáncer de pulmón (n = 52) seguido por los tumores de próstata (n = 13), mama (n = 7), colon (n = 4), estómago (n = 3), ovario (n = 2), riñón (n = 2), suprarrenal (n = 1), tiroides (n = 1), endometrio (n = 1), parótida (n = 1), carcinoma hepatobiliar (n = 2), leiomiosarcoma (n = 2) y tumor del...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research

Related Links:

We present a case where nocardial abscesses of lung and brain were initially suspected as lung cancer with brain metastases. The patient was treated with a combination of surgical resection and antimicrobial therapy with good outcome. PMID: 31969769 [PubMed - in process]
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
We describe a case of aggressive progression of TA in an infant. This child was the youngest to be affected with the disease as reported in the literature. A 3.5-month-old boy presented with cyanosis of both legs, tachycardia and antithrombin III deficiency. Computed tomography angiography (CTA) revealed thrombosis of distal aorta and both iliac arteries. Thrombectomy was performed at the level of both common femoral arteries. In addition, thigh amputation of the left leg had to be performed. TA was diagnosed postmortem with thrombosis of the distal aorta, its branches and upper mesenteric artery which was not occluded on ...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
We report the first case in Croatia where we used LCAP in the treatment of a patient with severe steroid-dependent UC. After 12 LCAP procedures, good clinical response was obtained and there were no significant adverse side effects noticed. The patient remained in clinical remission over two years in which he underwent regular follow ups at outpatient clinic. Over a 10-year follow-up period after LCAP, the patient had only occasional clinical symptoms of disease activity. The clinical course was complicated with the development of metastatic colorectal carcinoma, which points to the importance of regular disease monitoring...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
MEAN PLATELET VOLUME: AN OVERLOOKED HERALD OF MALIGNANT THYROID NODULES. Acta Clin Croat. 2019 Sep;58(3):417-420 Authors: Sit M, Aktas G, Ozer B, Kocak MZ, Erkus E, Erkol H, Yaman S, Savli H Abstract Physicians and surgeons pay much attention to evaluating thyroid nodules due to the malignant potential of these growths. Inflammation has a crucial role in the development of cancer. Increase in the mean platelet volume (MPV) has been described in various inflammatory conditions. Since some of thyroid nodules are malignant, we aimed to compare MPV values between patients with malignant and benign thyroid ...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
Publication date: Available online 23 January 2020Source: LWTAuthor(s): Xin-Yun Wang, Jing XieAbstractAcinetobacter johnsonii and Pseudomonas fluorescens are specific spoilage microorganisms (SSO) of aquatic products, and their metabolites are effective indicators for analyzing these two SSOs. However, the metabolome of a coculture of A. johnsonii and P. fluorescens is still unclear. The aim of this study was to investigate the metabolomic changes in A. johnsonii, P. fluorescens, and their co-culture by screening for metabolic markers. PCA and PLS-DA revealed that A, P, and AP groups were different from each other, indicat...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 23 January 2020Source: Food HydrocolloidsAuthor(s): Soumaya Boughriba, Nabil Souissi, Mourad Jridi, Suming Li, Moncef NasriAbstractHybrid composites films were prepared by the incorporation of titanium dioxide doped silver nanoparticles (TiO2–Ag NPs) at different concentrations (1, 2, 3 and 4 wt%) into Rhinobatos cemiculus gelatin (RCG) matrix. The microstructure analysis, realized by scanning electron microscopy and atomic force microscopy revealed a homogenous structure and a smooth surface of the composite films. The mechanical properties, light transmission and moisture conten...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
.
Source: Gut Microbes - Category: Microbiology Authors: Source Type: research
Publication date: Available online 23 January 2020Source: Journal of Physics and Chemistry of SolidsAuthor(s): Saviz Zarrin, Felora HeshmatpourAbstractIn the present investigation, we have designed highly active titanium dioxide nanohybrids modified by various additives such as niobium oxide (Nb2O5), tin (IV) oxide (SnO2), reduced graphene oxide (RGO) and ceramic (SiO2/Fe3O4/ZrO2) by combining the hydrothermal and sol-gel methods. The prepared samples i.e. TiO2/Nb2O5/SnO2/RGO, TiO2/Ceramic/SnO2/RGO, TiO2/Nb2O5/SnO2 and TiO2/Ceramic/SnO2 were identified by scanning electron microscopy (SEM), energy-dispersive X-ray spectros...
Source: Journal of Physics and Chemistry of Solids - Category: Physics Source Type: research
White-light scanning interferometry (WLSI) is an important measurement technique that has been widely used in three-dimensional profile ...
Source: Applied Optics - Category: Physics Authors: Source Type: research
Abstract In mammals, DNA methyltransferases transfer a methyl group from S-adenosylmethionine to the 5 position of cytosine in DNA. The product of this reaction, 5-methylcytosine (5mC), has many roles, particularly in suppressing transposable and repeat elements in DNA. Moreover, in many cellular systems, cell lineage specification is accompanied by DNA demethylation at the promoters of genes expressed at high levels in the differentiated cells. However, since direct cleavage of the C-C bond connecting the methyl group to the 5 position of cytosine is thermodynamically disfavoured, the question of whether DNA meth...
Source: Journal of Biosciences - Category: Biomedical Science Authors: Tags: J Biosci Source Type: research
More News: Adenocarcinoma | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Carcinoma of Unknown Primary | Colon Cancer | Colorectal Cancer | CT Scan | Endometrial Cancer | Gastric (Stomach) Cancer | Gastroenterology | Kidney Cancer | Leiomyosarcoma | Lung Cancer | Nuclear Medicine | Ovarian Cancer | Ovaries | PET Scan | Prostate Cancer | Renal Cell Carcinoma | Study | Thyroid | Thyroid Cancer