SMC recommends abatacept

The Scottish Medicines Consortium (SMC) has announced today that abatacept (Orencia®) has been accepted for use within NHS Scotland, in combination with methotrexate (MTX), as a first-line biologic agent for adults with rheumatoid arthritis (RA), after failure with two conventional DMARDs.
Source: Pharmacy Europe - Category: Drugs & Pharmacology Source Type: news

Related Links:

14-3-3η protein: a promising biomarker for rheumatoid arthritis. Biomark Med. 2018 Jul 19;: Authors: Zeng T, Tan L Abstract Effective management of rheumatoid arthritis (RA) depends on early identification followed by timely invention and proper monitoring of treatment responses which remain challenges facing rheumatologists for lacking biomarkers of high sensitivity and specificity. 14-3-3η has been reported to be a novel RA-related biomarker inducing the expression of multiple factors mediating the pathogenesis of RA, and increasing the diagnostic capture when combined with rheumatoid factor ...
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Publication date: Available online 20 July 2018Source: The Egyptian RheumatologistAuthor(s): Nermeen A. Fouad, Maha H. Nassr, Hanan M. Fathi, Othman M. Zaki, Ahmed A. Negm, Soha H. SenaraAbstractAim of the workTo determine the serum progranulin levels in rheumatoid arthritis (RA) patients and to study its relation with disease activity assessed clinically and by ultrasound (US).Patients and methodsThe study included 52 RA patients and 19 age and sex matched controls. Disease activity score (DAS-28) and modified health assessment questionaire were assessed. Progranulin was measured by ELISA. Ultrasound examination was perfo...
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
Authors: de Sire R, Rizzatti G, Ingravalle F, Pizzoferrato M, Petito V, Lopetuso L, Graziani C, de Sire A, Mentella MC, Mele MC, Gasbarrini A, Scaldaferri F Abstract In recent years, there has been an increasing interest on muscle wasting, considering the reduction of quality of life and the increase of morbidity and mortality associated. Sarcopenia and cachexia represent two conditions of reduction of muscle mass, sharing several elements involved in their pathogenesis, such as systemic inflammation, impaired muscle protein synthesis, increased muscle apoptosis, mitochondrial dysfunction in skeletal muscle tissue ...
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
See something of interest? Please share our postings with colleagues in your institutions! Spotlight The MAReport: Check out the Spring 2018 issue of the MAReport newsletter! This quarter, Academic Coordinator Elaina Vitale talked about using evidence-based resources to improve citations on Wikipedia, and her experience with NNLM’s first virtual Wikipedia Edit-a-thon. National Network of Libraries of Medicine News Dementia and Alzheimer’s Services @ Your Library – Midwest Matters, from GMR The next round of PubMed for Librarians begins August 29. Register for any (or all) of the PML classes to learn ...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
Conditions:   Huang Qi Gui Zhi Wu Wu Granule;   Rheumatoid Arthritis Interventions:   Drug: Huang qi gui zhi wu wu granule;   Drug: Huang qi gui zhi wu wu granule placebo Sponsor:   Cui xuejun Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Jong Y. Lee, Geum J. Kim, Jin K. Choi, Young-Ae Choi, Na-Hee Jeong, Pil-Hoon Park, Hyukjae Choi, Sang-Hyun Kim
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsThis study provides new options for assessing the CM diagnosis, which may improve RA treatment strategies. Identification of joint non-related symptoms and pathogenic external factors such as algor/“cold” may help understanding activation of specific immunological mechanisms, changes of capillary endothelium and the microcirculation disturbances. Overactivation of the functional defence mechanisms by algor/“cold” seem to be of utmost importance for RA symptoms.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Falls are one of the major health problems in adults with Rheumatoid Arthritis (RA). Interventions, such as the Otago Exercise Programme (OEP), can reduce falls in community dwelling adults by up to 35%. The c...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
Following the onset of rheumatoid arthritis (RA), patients experience a functional decline caused by various joint symptoms which affects their activities of daily living and can lead to reduced work productiv...
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
It is not known if sex-based disparities in immunological factors contribute to the disease process in rheumatoid arthritis (RA). Hence, we examined whether circulating T cell subset proportions and their asso...
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
More News: Abatacept | Arthritis | Drugs & Pharmacology | Methotrexate | Orencia | Rheumatoid Arthritis | Rheumatology