SMC recommends abatacept

The Scottish Medicines Consortium (SMC) has announced today that abatacept (Orencia®) has been accepted for use within NHS Scotland, in combination with methotrexate (MTX), as a first-line biologic agent for adults with rheumatoid arthritis (RA), after failure with two conventional DMARDs.
Source: Pharmacy Europe - Category: Drugs & Pharmacology Source Type: news

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Publication date: December 2018Source: Clinica Chimica Acta, Volume 487Author(s): Yukiko Nozawa, Hiroe Sato, Ayako Wakamatsu, Daisuke Kobayashi, Takeshi Nakatsue, Yoko Wada, Takeshi Kuroda, Junichiro James Kazama, Yoshiki Suzuki, Masaaki Nakano, Ichiei NaritaAbstractBackgroundPatients with rheumatoid arthritis (RA) often have reduced muscle mass. Estimated glomerular filtration ratio using the serum cystatin C concentration (eGFRcys) is more accurate than eGFR using the serum creatinine (eGFRcreat) because cystatin C is not influenced by muscle mass, but glucocorticoid therapy may affect serum cystatin C concentration.Meth...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
The exact causes of rheumatoid arthritis are unclear, but researchers have identified several risk factors. These range from genetic predispositions to gum disease. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news
Rheumatoid arthritis is a lifelong condition that causes pain, swelling, and inflammation in two or more joints. It can also affect the heart, lungs, and other parts of the body. It can lead to joint damage and difficulty functioning in daily life. Treatment can help manage the symptoms. Find out more.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news
Rheumatoid arthritis (RA) is an inflammatory disease that affects the joints and also produces symptoms throughout the body. Find out more about how to recognize RA.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news
Authors: Mohammed Yousef A, Abdelrahman SK, Elsayed Helmi I, Mohammed Eltaweel F, Elsayed Hamed W Abstract BACKGROUND: Autoantibodies are useful diagnostic tools for a variety of rheumatic autoimmune disorders. OBJECTIVE: The aim of the present study was to investigate autoantibodies against the 70-kD polypeptide of U1 ribonucleoprotein antibodies (RNP) in patients with rheumatoid arthritis (RA) and to investigate the relationship between anti-RNP and HLARD4 in RA patients. PATIENTS AND METHODS: In this prospective study, we studied 80 RA patients. The patients were classified according to 2010 ACR/EULAR Rh...
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research
AbstractBiological complexity and the need for personalized medicine means that biomarker development has become increasingly challenging. Thus, new paradigms for research need to be created that bring together a different classifier of individuals. One potential solution is collaboration between biomarker development and Chinese medicine pattern classification. In this article, two examples of rheumatoid arthritis are discussed, including a new biomarker candidate casein kinase 2 interacting protein 1 (CKIP-1) and a micro RNA 214. The authors obtained a “snapshot” of pattern classification with disease in biom...
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research
International Journal of Rheumatic Diseases, EarlyView.
Source: APLAR Journal of Rheumatology - Category: Rheumatology Authors: Source Type: research
International Journal of Rheumatic Diseases, EarlyView.
Source: APLAR Journal of Rheumatology - Category: Rheumatology Authors: Source Type: research
International Journal of Rheumatic Diseases, EarlyView.
Source: APLAR Journal of Rheumatology - Category: Rheumatology Authors: Source Type: research
International Journal of Rheumatic Diseases, EarlyView.
Source: APLAR Journal of Rheumatology - Category: Rheumatology Authors: Source Type: research
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