Developmental Expression of Monocarboxylate Transporter 1 and 4 in Rat Liver.

CONCLUSION: Our study elucidates the transcriptional and translational maturation patterns of MCT1, MCT4 and CD147 expression, with isoform- dependent differences in the liver. Changes in transporter expression during development may greatly influence drug distribution and clearance in pediatric populations.
PMID: 31361594 [PubMed - in process]

Source: J Pharm Pharm Sci - July 31, 2019 Category: Drugs & Pharmacology Authors: Ng M, Louie J, Cao J, Felmlee MA Tags: J Pharm Pharm Sci Source Type: research