Electroencephalographic spectral power as a marker of cortical function and disease severity in girls with Rett syndrome

ConclusionsIncreased power in lower frequency bands is consistent with previous studies demonstrating a “slowing” of the background EEG in Rett syndrome. This increase, particularly in the delta band, could represent abnormal cortical inhibition due to dysfunctional GABAergic signaling and could potentially be used as a marker of severity due to associations with more severe Rett syndrome phenotyp es.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research