Clinicopathologic features and lymph node metastatic characteristics in patients with adenocarcinoma manifesting as part-solid nodule exceeding 3cm in diameter

Ground glass nodule (GGN) is defined as a hazy increased opacity of the lung, with preservation of the bronchial and vascular margins, and the diameter is less than 3  cm (1). With the wide spread of computed tomography (CT) screening, more and more lung nodules with a ground glass opacity(GGO) component have been identified (2–4). And we will meet some GGN cases more than 3 cm occasionally. To our knowledge, few previous studies as of yet had focused on th e GGO exceeding 3 cm. Our study dedicatedly included GGO more than 3 cm, and we named it ground glass mass (GGM)>3  cm firstly.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research

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AbstractThere is little consensus in the literature about the administration of crizotinib in patients with end ‐stage renal disease undergoing hemodialysis. A 69‐year‐old male patient, who was receiving regular hemodialysis due to end‐stage renal disease, visited the hospital with symptoms of repeated abdominal pain. There was no suspicious finding of cancer within the thorax. After biopsy, the abdom inal lymph nodes were identified as adenocarcinoma originating from the lung following computed tomography (CT) scan, and ALK rearrangement was confirmed. The patient achieved a partial response following the administ...
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: CASE REPORT Source Type: research
Abstract Solitary splenic metastasis from primary lung cancer is extremely rare. Here, we demonstrated a solitary splenic metastasis of primary lung cancer that was difficult to distinguish from benign cystic disease. A 69-year-old-female was diagnosed as middle lobe lung cancer. Although preoperative abdominal computed tomography (CT) demonstrated a low-density splenic nodule, fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed no fluorodeoxyglucose uptake in the splenic nodule. Therefore, the nodule was diagnosed as benign cystic disease and middle lobe lobectomy was performed. Postoperative patho...
Source: Annals of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Cardiovasc Surg Source Type: research
AbstractPurposePrevious literature has reported contradicting results regarding the relationship between tumor volume changes during radiotherapy treatment for non-small cell lung cancer (NSCLC) patients and locoregional recurrence-free rate or overall survival. The aim of this study is to validate the results from a  previous study by using a different volume extraction procedure and evaluating an external validation dataset.MethodsFor two datasets of 94 and 141 NSCLC patients, gross tumor volumes were determined manually to investigate the relationship between tumor volume regression and locoregional control us...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
Conclusions: Inter-observer measurement variability for solid size was larger than for total size in lung adenocarcinoma. Large variability in group I indicated the difficulty of size measurement for low-grade malignant potential nodules such as adenocarcinoma in situ, minimally invasive adenocarcinoma, and early-stage invasive adenocarcinoma. The possibility of unavoidable size measurement variability should be recognized when deciding on surgical procedures for these diseases. PMID: 31463121 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Purpose: A common diagnostic dilemma in the assessment of small pulmonary nodules on computed tomography (CT) is in distinguishing benign intrapulmonary lymph nodes (IPLNs) from small primary pulmonary malignancies. Several CT features have been described of IPLNs, including attachment to a pleural surface. We had observed that IPLNs were often connected to a pulmonary vein and sought to evaluate the utility of this sign in discriminating IPLNs from lung adenocarcinomas. The frequency of other previously described CT signs of IPLNs was also compared with lung adenocarcinomas. Materials and Methods: We retrospectively ...
Source: Journal of Thoracic Imaging - Category: Radiology Tags: Original Articles Source Type: research
ConclusionThe iodine quantification parameters derived from enhanced DE-CT during the VP may be useful for distinguishing lung squamous cell carcinoma from adenocarcinoma.
Source: Academic Radiology - Category: Radiology Source Type: research
CONCLUSIONUsing 3D-MDCT, we could accurately divide A4 + 5 and safely perform the surgery.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We report a rare case of pulmonary IVLBCL accompanying lung cancer and interstitial lesions. A 73-year-old man with a history of pneumonia underwent a follow-up examination. Computed tomography revealed diffuse, bilateral ground-glass opacities (GGO) with a partial solid mass. Histologically, the mass consisted of adenocarcinoma. However, two other types of interstitial lesions were scattered throughout the resected lung: 1) peribronchovascular thickening with the aggregation of macrophages and anthracosis, and 2) alveolar septal thickening in the centrilobular area with atypical CD20-positive large cells in the capillarie...
Source: Journal of Clinical and Experimental Hematopathology : JCEH - Category: Hematology Tags: J Clin Exp Hematop Source Type: research
The maximum standardized uptake value (SUVmax) on positron emission tomography with [18  F] fluorodeoxyglucose (18 F-FDG PET) is a promising modality for predicting the prognosis and invasiveness of lung adenocarcinoma. [1,2] Especially in cases where tumors had pure-solid appearances on thin-section CT scans, the SUVmax on PET reflected the levels of tumor invasiveness and had a g reat effect on the prognoses. [3] The SUVmax has been shown to be associated with histology in lung cancer. The low SUVmax levels correlated well with lepidic predominance among clinical stage IA radiologic pure-solid lung adenocarcinoma patients.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
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Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
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