Oligohydramnios: should it be considered a risk factor for developmental dysplasia of the hip?

Breech, family history, first born and female sex are the main risk factors described for developmental dysplasia of the hip (DDH). Foot abnormalities and oligohydramnios have also been listed. Recent studies have discredited torticollis, multiple gestation pregnancy, mode of delivery and prematurity as risk factors. Definition of oligohydramnios in the literature is inconsistent. Our aim was to investigate the term oligohydramnios and evaluate whether it should be considered a risk factor for DDH. All live births in our institution between 2001 and 2014 were included. We identified all pregnancies classed as reduced amniotic fluid (AF) or oligohydramnios over that period. Data on DDH, breech presentation, female sex and positive family history were collected. The significance level was set to 5%. We identified 73 990 live births, 3408 pregnancies were classed as reduced AF or oligohydramnios. The incidence of DDH (Graf type IIb and higher) was 1: 1000 (75 babies, 18 bilateral). Oligohydramnios/reduced AF was found in 12 (16%) DDH babies. Breech presentation was found in 24 (32%), positive family history in 19 (25%) and female sex in 71 (94.7%). Oligohydramnios was found to be associated with a higher odds ratio (OR) for DDH [OR = 3.9, 95% confidence interval (CI): 2.1–7.3] as were breech presentation (OR = 10.6, 95% CI: 6.5–17.1) and female sex (OR = 19.1, 95% CI: 7–52.4). All examined risk factors showed statistical significance (P
Source: Journal of Pediatric Orthopaedics B - Category: Orthopaedics Tags: PELVIS & HIP Source Type: research

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Infants born at 23 to 27 weeks of pregnancy are most vulnerable.
Source: AJN - Category: Nursing Tags: In the News Source Type: research
Publication date: Available online 19 February 2020Source: The LancetAuthor(s): Håvard Ove Skjerven, Eva Maria Rehbinder, Riyas Vettukattil, Marissa LeBlanc, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Linn Landrø, Benjamin J Marsland, Knut Rudi, Kathrine Dønvold Sjøborg, Cilla Söderhäll, Anne Cathrine Staff, Kai-Håkon Carlsen, Anna Asarnoj, Karen Eline Stensby Bains, Oda C Lødrup Carlsen, Kim M Advocaat Endre, Peder Annæus Granlund, Johanne Uthus HermansenSummaryBackgroundSkin emollients applied during early infancy could prevent atopic dermatitis, and early comple...
Source: The Lancet - Category: General Medicine Source Type: research
In this long ‐term follow‐up of women with GDM, we found that 2‐hour glucose during OGTT at pregnancy predicted β‐cell function (as measured by ODI) 22 years post‐partum. Results of 2‐hour glucose during OGTT at pregnancy is a more useful indicator of long‐term metabolic risk. Most of the cases wh ich later converted to type 2 diabetes occurred within the first 15 years postpartum. AbstractAims/IntroductionWomen with gestational diabetes mellitus are at increased risk for type  2 diabetes. We characterized the association between maternal glycemia during pregnancy with long‐term outcomes.Methods a...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
ConclusionsThere is no clear evidence that the use of drugs during pregnancy and during the first year of life is associated with HSPM. Further well-designed prospective studies are needed.Clinical relevanceDetermining the etiological factors related to the development of HSPM would help to establish preventive protocols in patients at potential risk. As HSPM is predictive of molar incisor hypomineralisation (MIH), the application of preventive protocols would avoid complications in both the primary and permanent dentition.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
[UNFPA in WCA] Bamako, February 20, 2020, On Thursday, February 20, the Regional Office of the United Nations Population Fund  (UNFPA) for West and Central Africa (WCARO) is organizing a session on "Demography, Peace and Security" as part of the 20th edition of the Bamako Forum "Africa on the horizon 2040: between memories and futures" which is held from February 20 to 22, 2020 in Bamako, Mali under the High Patronage of the President of  the Republic of Mali, His Excellency Ibrahim Boubacar Keita.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
CONCLUSIONS: We found limited evidence of an association between prenatal traffic and ambient air pollution exposure and infant body composition. Suggestive associations between prenatal ozone exposure and early postnatal changes in body composition merit further investigation. PMID: 32069764 [PubMed - in process]
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
CONCLUSION: Based on all the statistical methods used, we demonstrated the effect of combined exposure to metals on the neurodevelopment of infants aged 6 months, with significant interaction between lead and mercury. PMID: 32069757 [PubMed - in process]
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
huhmacher M Abstract Maternal exposure to toxic and essential trace elements represents a surrogate of exposure to the unborn child. Variables of exposure as sociodemographic, lifestyles and diet may contribute to different exposure of pregnant women to specific trace elements. Blood, urine and cord blood samples of 53 pregnant women of the HEALS-EXHES cohort, recruited in Reus (Catalonia, Spain) between 2016 and 2017, were analysed for the concentrations of As, Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, Se and Zn. Univariate and multivariate models were built in order to assess associations between element concentrations in...
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
This study examined microstructural white matter as a possible mediator of the associations between prenatal phthalate exposure and behavior problems in preschool-aged children. METHODS: Data are from a subsample of a prospective pregnancy cohort, the Alberta Pregnancy Outcomes and Nutrition (APrON) study (n = 76). Mother-child pairs were included if mothers provided a second trimester urine sample, if the child completed a successful magnetic resonance imaging (MRI) scan at age 3-5 years, and if the Child Behavior Checklist was completed within 6 months of the MRI scan. Molar sums of high (HMWP) and low mol...
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
CONCLUSIONS: Based on the comprehensive pesticide exposome and metabolome wide associational study combined with meta-analysis, we found that prenatal exposure to β-HCH and mecarbam decreased birth weight via disrupting thyroid hormone metabolism and glyceraldehyde metabolism, providing new insights into the toxic effects of exposure to pesticides on birth outcomes. PMID: 32069748 [PubMed - in process]
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
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