Mid-term outcomes after percutaneous pulmonary valve implantation in complex right ventricular outflow tracts using the “folded” Melody® valve technique

ConclusionThe “folded valve technique” is a safe and feasible modification of the Melody® valve which provides favourable mid-term results without increased rate of valve related complications.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research

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Publication date: Available online 18 September 2019Source: Revista Portuguesa de Cardiologia (English Edition)Author(s): Isabel Durães Campos, Ana Rita Marques, Luciana Sousa, Sara Fonseca, Cátia Oliveira, Catarina Vieira, Isabel Apolinário, Ilídio BrandãoAbstractAn 83-year-old woman with a 10-year history of rheumatoid arthritis was admitted for urinary tract infection with exacerbation of chronic kidney disease and decompensated heart failure of unknown etiology. Transesophageal echocardiography (TEE) showed a vegetation involving the posterior mitral valve leaflet, and a hypothesis of...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Our studies reveal that the oral colonizer and cause of infective endocarditis Streptococcus oralis subsp. dentisani displays a striking monolateral distribution of surface fibrils. Furthermore, our data suggest that these fibrils impact the structure of adherent bacterial chains. Mutagenesis studies indicate that these fibrils are dependent on three serine-rich repeat proteins (SRRPs), here named fibril-associated protein A (FapA), FapB, and FapC, and that each SRRP forms a different fibril with a distinct distribution. SRRPs are a family of bacterial adhesins that have diverse roles in adhesion and that can bind to diffe...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Molecular Pathogenesis Source Type: research
WEDNESDAY, Sept. 18, 2019 -- The incidence of infective endocarditis (IE) associated with drug abuse (DA) increased from 2002 to 2016 in the United States, with increases seen in all regions, according to a study published online Sept. 18 in the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Finegoldia magna, a Gram-positive anaerobic coccus, is part of the human normal microbiota as a commensal of mucocutaneous surfaces. However, it remains an uncommon pathogen in infective endocarditis, with only e...
Source: Journal of Cardiothoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Case report Source Type: research
AbstractInfective endocarditis (IE) continues to be associated with high morbidity and mortality, even  when treated with optimal antibiotic regimens. The selection of treatment depends on the causative pathogen, its antibiotic susceptibility profile, local and systemic complications and the presence of prosthetic materials or devices. Standard therapy typically involves 4–6 weeks of intravenous (IV) bactericidal therapy. However, there are instances in which IV antibiotic administration may be challenging due to cost, complications of IV access, adverse side-effects of the medication or concerns for misuse...
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
Conclusions. The clinical spectrum of K. kristinae infections has recently widened. The increasing spread of this underestimated bacterium and its resistance to antibiotics represent a new challenge for public health, which requires specific actions to limit it. PMID: 31526454 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Publication date: Available online 12 September 2019Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Yi-Chin Chang, Shu-Fang Kuo, Chen-Hsiang Lee
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
This study compared the morbidity and mortality associated with IE depending on the microorganisms involved (BHS, ANHS, staphylococci, and enterococci).MethodsWe conducted a retrospective observational study between 2012 and 2017 in a single hospital in France. The endpoints were overall in-hospital mortality, 1-year mortality and the occurrence of complications.ResultsWe analyzed 316 episodes of definite IE including 150 (38%), 96 (25%), 46 (12%), and 24 cases (6%) of staphylococcal, ANHS, enterococcal, and BHS IE, respectively. In-hospital mortality was significantly higher in the staphylococcal (n = 40; 26...
Source: Infection - Category: Infectious Diseases Source Type: research
In conclusion, WB constitutes a promising and helpful method to diagnose E. faecalis or S. gallolyticus IE in patients with early antibiotic uptake and negative blood cultures.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Molecules, Vol. 24, Pages 3318: Molecular Mechanisms of Leonurus Cardiaca L. Extract Activity in Prevention of Staphylococcal Endocarditis—Study on in Vitro and ex Vivo Models Molecules doi: 10.3390/molecules24183318 Authors: Beata Sadowska Dariusz Laskowski Przemysław Bernat Bartłomiej Micota Marzena Więckowska-Szakiel Anna Podsędek Barbara Różalska Better understanding the mechanisms of Leonurus cardiaca L. extract (LCE) activity is necessary to prepare recommendations for the use of LCE-based herbal products for preventive/supportive purposes in case of infective endocarditis (IE) a...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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