Minimally important difference of the Fatigue Severity Scale and Modified Fatigue Impact Scale in people with Multiple Sclerosis

Conclusions: MID estimates derived from this study indicate that a difference of at least 0.45 points on the FSS or 4 points on the MFIS constitutes a clinically significant difference in fatigue. Therefore, these estimates represent a threshold value which can be used to interpret changes in the FSS and MFIS over time or in response to an intervention.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research