Mass Spectrometry for the  Study of Autism and Neurodevelopmental Disorders.

Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders. Adv Exp Med Biol. 2019;1140:477-499 Authors: Wormwood KL, Ngounou Wetie AG, Ryan JP, Darie CC, Woods AG Abstract Mass spectrometry (MS) has been increasingly used to study central nervous system (CNS) disorders, including autism spectrum disorders (ASDs). The first studies of ASD using MS focused on the identification of external toxins, but current research is more directed at understanding endogenous protein changes that occur in ASD (ASD proteomics). This chapter focuses on how MS has been used to study ASDs, with particular focus on proteomic analysis. Other neurodevelopmental disorders have been investigated using this technique, including genetic syndromes associated with autism such as fragile X syndrome (FXS) and Smith-Lemli-Opitz Syndrome (SLOS). PMID: 31347066 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research