TNFA -308G & gt;A and -238G & gt;A polymorphisms and risk to systemic sclerosis: impact on TNF- α serum levels, TNFA mRNA expression, and autoantibodies

In conclusion, the -308G>A polymorphism is a genetic marker of SSc susceptibility in population from southern Mexico, and it is associated with skin thickening and anti-fibrillarin antibodies. In addition, sTNF-α levels correlate positively with the anti-RNA pol III antibodies levels.
Source: Clinical and Experimental Medicine - Category: Research Source Type: research