Maximizing anti-HBs seroresponsiveness in  kidney transplant waitlist patients: 
A tertiary-center perspective

Maximizing anti-HBs seroresponsiveness in kidney transplant waitlist patients: 
A tertiary-center perspective
. Clin Nephrol. 2019 Jul 26;: Authors: Udomkarnjananun S, Townamchai N, Wattanatorn S, On-Yim L, Vanichanan J, Jutivorakool K, Avihingsanon Y, Praditpornsilpa K, Eiam-Ong S, Leelahavanichkul A Abstract BACKGROUND: Patients on dialysis are at risk of hepatitis B virus (HBV) infection, and antibodies against the hepatitis B surface antigen (anti-HBs) ≥ 10 IU/L are required. However, a high percentages of HBV vaccine nonresponders have been reported. We aimed to determine the optimal HBV vaccination protocol. MATERIALS AND METHODS: Kidney transplant waitlisted patients were followed for 12 months and categorized into two groups. Group A included patients with sustained anti-HBs ≥ 10 IU/L who did not require vaccination. Group B consisted of patients with anti-HBs
Source: Clinical Nephrology - Category: Urology & Nephrology Authors: Tags: Clin Nephrol Source Type: research

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WEST NILE VIRUS INFECTION WITH NEUROLOGICAL DISORDERS: A CASE REPORT AND A BRIEF REVIEW OF THE SITUATION IN BULGARIA. Acta Clin Croat. 2019 Sep;58(3):546-549 Authors: Baymakova M, Christova I, Panayotova E, Trifonova I, Chobanov A, Daskalov I, Popov GT, Plochev K Abstract A case of a 66-year-old man with West Nile neuroinvassive disease manifested with fever, weakness, fatigue, consciousness disorders and underlying diabetes mellitus type 2 and cardiovascular diseases is presented. Laboratory data showed elevated erythrocyte sedimentation rate and fibrinogen. Serological tests revealed West Nile virus ...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
This study has been carried out to examine the effect of SSF by Rhizopus oryzae on the bioactive content, bioactivity, bioaccessibility and bioavailability of 4 different varieties of rice bran. In vitro digestion with dialysis was carried out to assess the bioavailability and bioaccessibility of rice bran bioactives. Methanolic extracts and digested fractions of fermented and unfermented rice brans were analyzed for total phenolic (TPC), flavonoid (TF), carotenoid (TC), and total anthocyanin content (TAC). Additionally, antioxidant activity, anti-inflammatory property and the anti-diabetic property was also evaluated. The...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 23 January 2020Source: Life SciencesAuthor(s): Irshad Ahmad, Muddasarul HodaAbstractResveratrol is an important phenolic phytochemical from the therapeutic perspective. It has therapeutic impacts over wide range of diseases, especially the ones related to oxidative stress. Resveratrol, being primarily a potent anti-oxidant phytochemical, has significant impact against major diseases as inflammatory disorders, diabetes, and cancer. In the current review article, we intend to highlight the molecular aspects of the mechanism of action of resveratrol against major diabetic implications, namel...
Source: Life Sciences - Category: Biology Source Type: research
The Gaithersburg biotech's latest move reflects its fundamental strategy: Watch for opportunities to address a virus outbreak.
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
In this study, we investigated different bioactive compounds in marine resources that may be potentially useful in treating or managing diabetes, as well as describe the various therapeutic mechanisms affecting diabetes and its complications, including inhibition of α-amylase, α-glucosidase, β -glucosidase, glycogen synthase kinase 3β (GSK-3β), lipase, aldose reductase, protein tyrosine phosphatases 1B (PTP1B) and dipeptidyl peptidase IV   (DPP-4), prevention of insulin resistance, increased phosphorylation of the AMP-activated protein kinase (AMPK) and adjusting the metabolism of glucose ...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
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Source: Thermochimica Acta - Category: Chemistry Source Type: research
Publication date: Available online 23 January 2020Source: Journal of Energy ChemistryAuthor(s): Guli Zhou, Jinman Yang, Xingwang Zhu, Qidi Li, Wiam El-alami, Chongtai Wang, Yuanbin She, Junchao Qian, Hui Xu, Huaming LiAbstractBlack phosphorus (BP), an interesting and multi-functional non-metal material, has attracted widespread attention. In this work, 2D BP/2D g-C3N4 heterostructure had been fabricated at extremely low temperature, which was used to reduce CO2 for the first time. With introduction of 2D BP, the separation of photogenerated holes and electrons was extremely boosted, and composites showed excellent photocat...
Source: Journal of Energy Chemistry - Category: Chemistry Source Type: research
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Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
CONCLUSION: The diagnosis of PIGCH remains clinically challenging and requires a high index of suspicion as well as a thorough history, physical examination, serological workup and liver biopsy. Treatment of the underlying cause can result in clinical stability in a large number of cases. PMID: 31966907 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
CONCLUSIONS: Dpcr greatly improved the sensitivity and specificity of cccDNA detection. Host CDK activities are likely required for cccDNA synthesis. dPCR can potentially be applied for drug screening for effective cccDNA inhibitors. PMID: 31964596 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
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